Gastric primary non-Hodgkin lymphoma: a case report and literature review

Non-Hodgkin malignant lymphomas represent a heterogeneous group of monoclonal tumors developing from cells belonging to the immune system. Primary gastric lymphomas are defined as those malignant limphoproliferative diseases whose initial symptoms are located in the stomach or tumor mass located in the stomach. This paper aims to present a new case of primary gastric non Hodgkin lymphoma diagnosed by histologic and immunohistochemical examination of a partial gastrectomy specimen. The patient is a 51-years old man with a history of smoking, hospitalized for asthenia, hematemesis and melena. Microscopically the tumor consisted of mature small lymphocytes admixed with plasmocitoid lymphocytes and mature plasmocytes. Some of the tumoral cells showed citoplasmatic pas positive inclusions. Immunohistochemical stains were strongly positive for CD20 and 30-40% positive for Ki67.Based on the clinical and histological findings, a diagnosis of gastric primary non-Hodgkin lymphoma was established.