<abstract xmlns="http://www.w3.org/1999/xhtml"><p> The purpose of the present study was to analyse the changes in concentrations of total proteins, albumin, globulins and albumin/globulin ratio in dogs with experimentally induced acute inflammation. The study was performed on 9 mongrel dogs (experimental group) and 6 mongrel dogs (control group) at the age of 2 years and body weight 12-15 kg. The acute inflammation was reproduced by inoculation of 2 ml turpentine oil in the lumbar region subcutaneously and in same quantity saline in control dogs. Blood samples were collected into heparinized tubes before inoculation (hour 0) then at hours 6, 24, 48, 72 and on days 7, 14, 21. The statistical analysis of the data was performed using one way analysis of variance (ANOVA). The level of albumin statistically decreased in the experimental dogs from at 72nd h to day 14 while the concentration of globulins increased from the 72nd h to day 21. On days 7 and 14 the albumin/globulin ratio slightly decreased. During the whole post inoculation period the values of total protein have not changed. The dates of the present study confirm that albumin, albumin/globulin ratio and globulins are sensitive factors in inflammatory conditions in dogs.</p></abstract>

The purpose of the present study was to analyse the changes in concentrations of total proteins, albumin, globulins and albumin/globulin ratio in dogs with experimentally induced acute inflammation. The study was performed on 9 mongrel dogs (experimental group) and 6 mongrel dogs (control group) at the age of 2 years and body weight 12-15 kg. The acute inflammation was reproduced by inoculation of 2 ml turpentine oil in the lumbar region subcutaneously and in same quantity saline in control dogs. Blood samples were collected into heparinized tubes before inoculation (hour 0) then at hours 6, 24, 48, 72 and on days 7, 14, 21. The statistical analysis of the data was performed using one way analysis of variance (ANOVA). The level of albumin statistically decreased in the experimental dogs from at 72nd h to day 14 while the concentration of globulins increased from the 72nd h to day 21. On days 7 and 14 the albumin/globulin ratio slightly decreased. During the whole post inoculation period the values of total protein have not changed. The dates of the present study confirm that albumin, albumin/globulin ratio and globulins are sensitive factors in inflammatory conditions in dogs.

Changes in the Concentrations of Some Plasma Proteins During Acute Inflammation in Dogs

Advanced Research in Life Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

The purpose of the present study was to analyse the changes in concentrations of total proteins, albumin, globulins and albumin/globulin ratio in dogs with...

Changes in the Concentrations of Some Plasma Proteins During Acute Inflammation in Dogs

Published Online: Jul 14, 2017

Page range: 85 - 89

Accepted: Jun 01, 2017

DOI: https://doi.org/10.1515/arls-2017-0015

Keywords
plasma proteins, acute inflammation, dogs

© 2017

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Changes in the Concentrations of Some Plasma Proteins During Acute Inflammation in Dogs

Published Online: Jul 14, 2017

Page range: 85 - 89

Accepted: Jun 01, 2017

DOI: https://doi.org/10.1515/arls-2017-0015

Keywordsplasma proteins, acute inflammation, dogs

© 2017

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
plasma proteins, acute inflammation, dogs