<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Objective</bold>: Regeneration is defined as a reconstruction of a lost part of the body in such a way that the structure and function of the lost tissue are completely restored. The aim of this study is to compare the clinical outcomes of intrabony defects treatment using regenerative periodontal therapy with enamel matrix proteins (Emdogain, EMD) with a control group.<bold>Methods</bold>: Ten patients with chronic periodontitis were included in this randomized, controlled clinical study. Two groups received conservative periodontal therapy. In the test group, different teeth received regenerative treatment with EMD. In the control group teeth received solely conservative periodontal therapy. Pocket depth probing (PD) and bone reduction (based on X rays) were registered at baseline and after eight months in both groups. In the control group<bold>Results</bold>: Both groups showed a significant reduction of PD. The teeth treated with EMD showed a significant attachment gain. Within the test group, the radiographic examination of the teeth treated with EMD showed no significant change, whereas the teeth in the control group showed significant bone reduction.<bold>Conclusions:</bold> Intrabony defects in teeth treaded with EMD exhibit a substantially higher gain in clinical attachment and defect filling. The use of EMD in dental practice can prevent further bone loss.</abstract>

Objective: Regeneration is defined as a reconstruction of a lost part of the body in such a way that the structure and function of the lost tissue are completely restored. The aim of this study is to compare the clinical outcomes of intrabony defects treatment using regenerative periodontal therapy with enamel matrix proteins (Emdogain, EMD) with a control group.Methods: Ten patients with chronic periodontitis were included in this randomized, controlled clinical study. Two groups received conservative periodontal therapy. In the test group, different teeth received regenerative treatment with EMD. In the control group teeth received solely conservative periodontal therapy. Pocket depth probing (PD) and bone reduction (based on X rays) were registered at baseline and after eight months in both groups. In the control groupResults: Both groups showed a significant reduction of PD. The teeth treated with EMD showed a significant attachment gain. Within the test group, the radiographic examination of the teeth treated with EMD showed no significant change, whereas the teeth in the control group showed significant bone reduction.Conclusions: Intrabony defects in teeth treaded with EMD exhibit a substantially higher gain in clinical attachment and defect filling. The use of EMD in dental practice can prevent further bone loss.

Clinical Outcomes after Regenerative Periodontal Therapy with Emdogain

University of Medicine and Pharmacy Tirgu Mures

Department of Oral and Maxillofacial Surgery, Faculty of Dental Medicine

Department of Tooth and Dental Arch Morphology, Faculty of Dental Medicine

Department of Odontology and Oral Pathology, Faculty of Dental Medicine

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Clinical Outcomes after Regenerative Periodontal Therapy with Emdogain"}

Objective: Regeneration is defined as a reconstruction of a lost part of the body in such a way that the structure and function of the lost tissue are...

Clinical Outcomes after Regenerative Periodontal Therapy with Emdogain

Published Online: Sep 23, 2017

Page range: 136 - 139

Received: Feb 28, 2017

Accepted: Apr 27, 2017

DOI: https://doi.org/10.1515/amma-2017-0015

Keywords
chronic periodontitis, regeneration, emdogain, intrabony defects

© 2017 Gabriela Felicia Beresescu et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Clinical Outcomes after Regenerative Periodontal Therapy with Emdogain

Published Online: Sep 23, 2017

Page range: 136 - 139

Received: Feb 28, 2017

Accepted: Apr 27, 2017

DOI: https://doi.org/10.1515/amma-2017-0015

Keywordschronic periodontitis, regeneration, emdogain, intrabony defects

© 2017 Gabriela Felicia Beresescu et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
chronic periodontitis, regeneration, emdogain, intrabony defects