Correlations of Endogenous Testosterone and DHEA-S in Peripheral Arterial Disease

1. Alzamora MT, Forés R, Pera G et al. Incidence of peripheral arterial disease in the ARTPER population cohort after 5 years of follow-up. BMC Cardiovasc Disord. 2016;16(1):8 DOI:10.1186/s12872-015-0170-610.1186/s12872-015-0170-6Search in Google Scholar

2. George J, Rapsomaniki E, Pujades-Rodriguez M et al. How Does Cardiovascular Disease First Present in Women and Men? Incidence of 12 Cardiovascular Diseases in a Contemporary Cohort of 1 937 360 People. Circulation. 2015;132:1320-1328.10.1161/CIRCULATIONAHA.114.013797Search in Google Scholar

3. Criqui MH, Aboyans V. Epidemiology of Peripheral Artery Disease. Circ Res. 2015;116:1509-1526.10.1161/CIRCRESAHA.116.303849Search in Google Scholar

4. Hak AE, Witteman JCM, De Jong FH et al. Low levels of Endogenous Androgens Increase the Risk of Atherosclerosis in Elderly Men: The Rotterdam Study. The Journal of Clinical Endocrinology & Metabolism. 2002;87(8):3632-3639.10.1210/jcem.87.8.8762Search in Google Scholar

5. Freeman BM, Mountain DJ, Brock TC et al. Low testosterone elevates interleukin family cytokines in a rodent model: a possible mechanism for the potentiation of vascular disease in androgen-deficient males. J Surg Res. 2014;190(1):319-27.10.1016/j.jss.2014.03.017Search in Google Scholar

6. Haring R, Travison TG, Bhasin S et al. Relation between sex hormone concentrations, peripheral arterial disease, and change in ankle-brachial index: findings from the Framingham Heart Study. J Clin Endocrinol Metab. 2011,96(12):3724-32.10.1210/jc.2011-1068Search in Google Scholar

7. Kiechl S, Willeit J, Bonora E, Schwarz S, Xu Q. No Association Between Dehydroepiandrosterone Sulfate and Development Atherosclerosis in a Prospective Population Study (Bruneck Study). Arterioscler Thromb Vasc Biol. 2000;20:1094-1100.10.1161/01.ATV.20.4.1094Search in Google Scholar

8. Price JF, Lee AJ, Fowkes FG. Steroid sex hormones and peripheral arterial disease in the Edinburgh Artery Study. Steroids. 1997;62(12):789-94.10.1016/S0039-128X(97)00103-7Search in Google Scholar

9. Yeap BB, Alfonso H, Chubb SA et al. Lower plasma testosterone or dihydrotestosterone, but not estradiol, is associated with symptoms of intermittent claudication in older men. Clin Endocrinol (Oxf). 2013;79(5):725-32.10.1111/cen.1220823509861Search in Google Scholar

10. Bataille V, Perret B, Evans A. et al. Sex hormone-binding globulin is a major determinant of the lipid profile: the PRIME study. Atherosclerosis. 2005;179(2):369-7310.1016/j.atherosclerosis.2004.10.02915777555Search in Google Scholar

11. de Keyser CE, de Lima FV, de Jong FH et al. Use of statins is associated with lower serum total and non-sex hormone-binding globulin-bound testosterone levels in male participants of the Rotterdam Study. Eur J Endocrinol. 2015;173(2):155-65.10.1530/EJE-14-106126034077Search in Google Scholar

12. Malkin CJ, Pugh PJ, Jones RD, Jones TH, Channer KS. Testosterone as a protective factor against atherosclerosis –immunomodulation and influence upon plaque development and stability. Journal of Endocrinology, 2003;178:373–380.10.1677/joe.0.178037312967330Search in Google Scholar

13. Jin H, Lin J, Fu L et al. Physiological testosterone stimulates tissue plasminogen activator and tissue factor pathway inhibitor and inhibits plasminogen activator inhibitor type 1 release in endothelial cells. Biochem. Cell Biol, 2007;85(2):246-251.Search in Google Scholar

14. Jones RD, Jones TH, Channer KS. The influence of testosterone upon vascular reactivity. European Journal of Endocrinology, 2004;151:29-37.10.1530/eje.0.151002915248819Search in Google Scholar

15. Price J, Leng GC. Steroid sex hormones for lower limb atherosclerosis. Cochrane Database Syst Rev. 2012;10:CD000188 doi: 10.1002/14651858.CD000188.pub210.1002/14651858.CD000188.pub2695656023076884Search in Google Scholar

16. Tivesten A, Mellström D, Jutberger H. et al. Low serum testosterone and high serum estradiol associate with lower extremity peripheral arterial disease in elderly men. The MrOS Study in Sweden. J. Am. Col. Cardiol. 2007;50(11):1070-1076.Search in Google Scholar