<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Graham Little-Lassueur Syndrome (GLLS) is considered a form of lichen planopilaris which associates follicular lichen planus, cicatricial alopecia of the scalp and noncicatricial alopecia of the axillary and/or pubic regions. We present the case of a 47 years old female patient, known for 5 years with chronic hepatitis C and a poor therapeutic control of the disease due to Interferon intolerance. She presented to our clinic for the occurrence on the shins of some well-defined, intensely pruritic erythematous plaques, covered with thick scales, with a verrucous appearance, accompanied by excoriations. The skin biopsy reveal hypertrophic lichen planus on the shins and lichen planopilaris on the scalp. The patient was treated with systemic antihystamines, topical corticosteroids and salicylic acid under occlusion, emollients, phototherapy UVB narrow band 4 sessions/week for 3 weeks, cryotherapy. From our knowledge this is the first case of GLLS associated with chronic viral hepatis C.</p></abstract>

Graham Little-Lassueur Syndrome (GLLS) is considered a form of lichen planopilaris which associates follicular lichen planus, cicatricial alopecia of the scalp and noncicatricial alopecia of the axillary and/or pubic regions. We present the case of a 47 years old female patient, known for 5 years with chronic hepatitis C and a poor therapeutic control of the disease due to Interferon intolerance. She presented to our clinic for the occurrence on the shins of some well-defined, intensely pruritic erythematous plaques, covered with thick scales, with a verrucous appearance, accompanied by excoriations. The skin biopsy reveal hypertrophic lichen planus on the shins and lichen planopilaris on the scalp. The patient was treated with systemic antihystamines, topical corticosteroids and salicylic acid under occlusion, emollients, phototherapy UVB narrow band 4 sessions/week for 3 weeks, cryotherapy. From our knowledge this is the first case of GLLS associated with chronic viral hepatis C.

Graham Little-Lassueur Syndrome with Hypertrophic Lichen Planus in a Patient with Chronic Hepatitis C

Dermatology Clinic, County Hospital of Tîrgu Mureș, Romania

Department of Public Health and Medicines Management, Tîrgu Mureș

Dermatology Clinic, Emergency Military Hospital, Bucharest, Romania

Anesthesiology and Intensive Care medicine Clinic, Emergency County Hospital of Tîrgu Mureș

University of Medicine and Pharmacy Tîrgu Mureș, Romania

Department of Dermatology, University of Medicine and Pharmacy Tîrgu Mureș, Romania

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Graham Little-Lassueur Syndrome (GLLS) is considered a form of lichen planopilaris which associates follicular lichen planus, cicatricial alopecia of the scalp...

Graham Little-Lassueur Syndrome with Hypertrophic Lichen Planus in a Patient with Chronic Hepatitis C

Published Online: Feb 09, 2016

Page range: 149 - 151

Received: Jul 30, 2015

Accepted: Sep 11, 2015

DOI: https://doi.org/10.1515/amma-2015-0089

Keywords
Graham Little Lassueur syndrome, hypertrophic lichen planus, chronic hepatitis C

© by Florin Buicu

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Graham Little-Lassueur Syndrome with Hypertrophic Lichen Planus in a Patient with Chronic Hepatitis C

Published Online: Feb 09, 2016

Page range: 149 - 151

Received: Jul 30, 2015

Accepted: Sep 11, 2015

DOI: https://doi.org/10.1515/amma-2015-0089

KeywordsGraham Little Lassueur syndrome, hypertrophic lichen planus, chronic hepatitis C

© by Florin Buicu

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
Graham Little Lassueur syndrome, hypertrophic lichen planus, chronic hepatitis C