<abstract xmlns="http://www.w3.org/1999/xhtml">The aim of the current study was to find any possible associations between elements of metabolic syndrome and echocardiographic characteristics (grade of diastolic dysfunction) in normoponderal and overweight patients with heart failure with preserved ejection fraction.A retrospective observational analytical study was performed on 130 patients presenting heart failure with documented ejection fraction over 50%. They were divided into two groups based on their body mass index. The first group included 56 normal weight patients and the second group included 74 overweight patients. Elements of the metabolic syndrome analysed in the current study were arterial hypertension, high triglyceride levels, low HDL-cholesterol and diabetes.None of the components of metabolic syndrome alone had a role in the evolution of diastolic dysfunction in either group. Three or four elements present in obese patients were negatively associated with grade 2 diastolic dysfunction, high values of blood pressure (over 180/110 mmHg) were more often encountered in obese patients with first and second grade of diastolic dysfunction.</abstract>

The aim of the current study was to find any possible associations between elements of metabolic syndrome and echocardiographic characteristics (grade of diastolic dysfunction) in normoponderal and overweight patients with heart failure with preserved ejection fraction.A retrospective observational analytical study was performed on 130 patients presenting heart failure with documented ejection fraction over 50%. They were divided into two groups based on their body mass index. The first group included 56 normal weight patients and the second group included 74 overweight patients. Elements of the metabolic syndrome analysed in the current study were arterial hypertension, high triglyceride levels, low HDL-cholesterol and diabetes.None of the components of metabolic syndrome alone had a role in the evolution of diastolic dysfunction in either group. Three or four elements present in obese patients were negatively associated with grade 2 diastolic dysfunction, high values of blood pressure (over 180/110 mmHg) were more often encountered in obese patients with first and second grade of diastolic dysfunction.

Association of Heart Failure with Preserved Ejection Fraction and Components of Metabolic Syndrome

Department of Nephrology, University of Medicine and Pharmacy, Tirgu-Mures, Romania

Department of Urology, University of Medicine and Pharmacy, Tirgu-Mures, Romania

Department of Physiology, University of Medicine and Pharmacy, Tirgu-Mures, Romania

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The aim of the current study was to find any possible associations between elements of metabolic syndrome and echocardiographic characteristics (grade of...

Association of Heart Failure with Preserved Ejection Fraction and Components of Metabolic Syndrome

Published Online: Jan 19, 2016

Page range: 261 - 264

Received: Jun 23, 2015

Accepted: Aug 03, 2015

DOI: https://doi.org/10.1515/amma-2015-0078

Keywords
diastolic dysfunction, metabolic syndrome, body mass index

© 2015 Cerghizan Anda-Mihaela et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Association of Heart Failure with Preserved Ejection Fraction and Components of Metabolic Syndrome

Published Online: Jan 19, 2016

Page range: 261 - 264

Received: Jun 23, 2015

Accepted: Aug 03, 2015

DOI: https://doi.org/10.1515/amma-2015-0078

Keywordsdiastolic dysfunction, metabolic syndrome, body mass index

© 2015 Cerghizan Anda-Mihaela et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
diastolic dysfunction, metabolic syndrome, body mass index