<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The diagnosis of dysplasia and early neoplasia in Barrett’s esophagus by conventional endoscopy is based on a four- quadrant random biopsies protocol that is prone to sampling errors. Novel endoscopic techniques have been developed to enhance the detection of premalignant and malignant lesions by real time assessment of microvasculare architecture and mucosal structure. Chromoendoscopy with magnification has improved the visualization of lesions, but the dye application impairs a clear evaluation of vascular network. Narrow band imaging endoscopy enhances vascular imaging by using narrow bandwidth lights, with penetration to superficial mucosal structures. Different classification systems of mucosal and vascular patterns have been developed to improve the diagnostic accuracy of non-dysplastic and dysplastic BE, as well as of early esophageal cancer. This article is focused on both the clinical benefits and controversies surrounding conventional and advanced endoscopic methods used for screening and surveillance of patients with Barrett’s esophagus. Current evidence shows that the adoption of new technology in routine practice requires a high level of performance as well as the standardization of various classification systems.</p></abstract>

The diagnosis of dysplasia and early neoplasia in Barrett’s esophagus by conventional endoscopy is based on a four- quadrant random biopsies protocol that is prone to sampling errors. Novel endoscopic techniques have been developed to enhance the detection of premalignant and malignant lesions by real time assessment of microvasculare architecture and mucosal structure. Chromoendoscopy with magnification has improved the visualization of lesions, but the dye application impairs a clear evaluation of vascular network. Narrow band imaging endoscopy enhances vascular imaging by using narrow bandwidth lights, with penetration to superficial mucosal structures. Different classification systems of mucosal and vascular patterns have been developed to improve the diagnostic accuracy of non-dysplastic and dysplastic BE, as well as of early esophageal cancer. This article is focused on both the clinical benefits and controversies surrounding conventional and advanced endoscopic methods used for screening and surveillance of patients with Barrett’s esophagus. Current evidence shows that the adoption of new technology in routine practice requires a high level of performance as well as the standardization of various classification systems.

The usefulness of white light endoscopy, narrow band imaging, and magnification for the optimization of diagnosis in Barrett’s esophagus

Department of Gastroenterology, University of Medicine and Pharmacy Tirgu Mures, Romania

University of Medicine and Pharmacy Tirgu Mures, Tirgu Mures County Emergency Hospital, Tirgu Mures, Romania

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The diagnosis of dysplasia and early neoplasia in Barrett’s esophagus by conventional endoscopy is based on a four- quadrant random biopsies protocol that is...

The usefulness of white light endoscopy, narrow band imaging, and magnification for the optimization of diagnosis in Barrett’s esophagus

Published Online: Jan 27, 2015

Page range: 244 - 248

Received: Oct 30, 2014

Accepted: Dec 07, 2014

DOI: https://doi.org/10.1515/amma-2015-0002

Keywords
endoscopy, Barrett’s esophagus, dysplasia, early cancer

© by Alina Boeriu

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The usefulness of white light endoscopy, narrow band imaging, and magnification for the optimization of diagnosis in Barrett’s esophagus

Published Online: Jan 27, 2015

Page range: 244 - 248

Received: Oct 30, 2014

Accepted: Dec 07, 2014

DOI: https://doi.org/10.1515/amma-2015-0002

Keywordsendoscopy, Barrett’s esophagus, dysplasia, early cancer

© by Alina Boeriu

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
endoscopy, Barrett’s esophagus, dysplasia, early cancer