<abstract xmlns="http://www.w3.org/1999/xhtml"><p>CRP and WBC are the most widely used markers of inflammation in veterinary clinical diagnosis. Also, PCT is a specific APP marker of bacterial diseases in humans. This study evaluated the levels of PCT, CRP and WBC during postoperative monitoring of bitches undergoing ovariohysterectomy. Thirteen adult clinically healthy female crossbreed dogs aged between 7-24 months were used in the study. Ovariohysterectomy was performed via medial laparotomy using routine procedures. Blood samples were collected from the cephalic vein at 1, 4 and 7 days after surgery (post-op period). Mean serum concentration of PCT, CRP and WBC levels were increased after the surgery. CRP concentrations and WBC counts were increased significantly (p&lt;0.001) on the first day after the operation and decreased to basal values. However, the PCT rise was not significant. CRP and WBC levels increased rapidly and decreased to normal values in dogs with ovariohysterectomy. CRP and WBC may be of help to determine the possible postoperative complications. Besides, aseptic surgical trauma did not affect PCT levels in dogs. Future studies are needed on canine PCT response focusing on specific bacterial infections.</p></abstract>

CRP and WBC are the most widely used markers of inflammation in veterinary clinical diagnosis. Also, PCT is a specific APP marker of bacterial diseases in humans. This study evaluated the levels of PCT, CRP and WBC during postoperative monitoring of bitches undergoing ovariohysterectomy. Thirteen adult clinically healthy female crossbreed dogs aged between 7-24 months were used in the study. Ovariohysterectomy was performed via medial laparotomy using routine procedures. Blood samples were collected from the cephalic vein at 1, 4 and 7 days after surgery (post-op period). Mean serum concentration of PCT, CRP and WBC levels were increased after the surgery. CRP concentrations and WBC counts were increased significantly (p<0.001) on the first day after the operation and decreased to basal values. However, the PCT rise was not significant. CRP and WBC levels increased rapidly and decreased to normal values in dogs with ovariohysterectomy. CRP and WBC may be of help to determine the possible postoperative complications. Besides, aseptic surgical trauma did not affect PCT levels in dogs. Future studies are needed on canine PCT response focusing on specific bacterial infections.

Procalcitonin is not a marker of sterile inflammation in dogs after ovariohysterectomy

Adnan Menderes University Faculty of Veterinary Medicine, Department of Biochemistry, Aydın,

Acta Veterinaria

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

CRP and WBC are the most widely used markers of inflammation in veterinary clinical diagnosis. Also, PCT is a specific APP marker of bacterial diseases in...

Procalcitonin is not a marker of sterile inflammation in dogs after ovariohysterectomy

Published Online: Mar 30, 2017

Page range: 131 - 136

Received: Jun 09, 2016

Accepted: Nov 04, 2016

DOI: https://doi.org/10.1515/acve-2017-0012

Keywords
Procalcitonine, C-reactive protein, WBC, dog, ovariohysterectomy

© 2017 Gürbüz Hasan Oğuz et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Procalcitonin is not a marker of sterile inflammation in dogs after ovariohysterectomy

Published Online: Mar 30, 2017

Page range: 131 - 136

Received: Jun 09, 2016

Accepted: Nov 04, 2016

DOI: https://doi.org/10.1515/acve-2017-0012

KeywordsProcalcitonine, C-reactive protein, WBC, dog, ovariohysterectomy

© 2017 Gürbüz Hasan Oğuz et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Procalcitonine, C-reactive protein, WBC, dog, ovariohysterectomy