<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The Institute of Virology, Vaccines and Sera Torlak was established in 1927, while the first vaccine was produced in the Institute in 1930. Vaccines production implies using experimental animals, including mice, in in-process controls. The laboratory mice which have been in use in Torlak Institute from the very beginning belong to Swiss albino outbred stock. This stock, which has been in use for more than 80 years contains a large number of mice maintained at all times, was recently named Intor:Swiss. Biological characteristics of Intor:Swiss stock, are presented in this paper for the first time. Taking into account the presented characteristics, the Institute Torlak’s Swiss mice are suitable for use in pharmaceutical studies, vaccine development research and basic research, as well as in toxicological studies. The publication of data on the Intor:Swiss mice represents a contribution to the international scientific community, since it offers the possibility for obtaining an additional outbred mouse stock for research.</p></abstract>

The Institute of Virology, Vaccines and Sera Torlak was established in 1927, while the first vaccine was produced in the Institute in 1930. Vaccines production implies using experimental animals, including mice, in in-process controls. The laboratory mice which have been in use in Torlak Institute from the very beginning belong to Swiss albino outbred stock. This stock, which has been in use for more than 80 years contains a large number of mice maintained at all times, was recently named Intor:Swiss. Biological characteristics of Intor:Swiss stock, are presented in this paper for the first time. Taking into account the presented characteristics, the Institute Torlak’s Swiss mice are suitable for use in pharmaceutical studies, vaccine development research and basic research, as well as in toxicological studies. The publication of data on the Intor:Swiss mice represents a contribution to the international scientific community, since it offers the possibility for obtaining an additional outbred mouse stock for research.

Characterization of Intor:Swiss Albino Mice Adopted in the Institute of Virology, Vaccines and Sera – Torlak, Belgrade in the Early Twentieth Century

Institute of Virology, Vaccines and Sera – Torlak, Department of Research and Development, Vojvode Stepe 458, Belgrade,

Institute for Medical research Belgrade (IMI) BU, Dr Subotića starijeg 4, 11000 Belgrade,

Institute of Virology, Vaccines and Sera – Torlak, Department of Laboratory Animal Breeding, Vojvode Stepe 458, Belgrade,

Gilead Sciences, Inc. 4049 Avenida de la Plata, Oceanside, CA,

Acta Veterinaria

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The Institute of Virology, Vaccines and Sera Torlak was established in 1927, while the first vaccine was produced in the Institute in 1930. Vaccines production...

Characterization of Intor:Swiss Albino Mice Adopted in the Institute of Virology, Vaccines and Sera – Torlak, Belgrade in the Early Twentieth Century

Published Online: Sep 29, 2016

Page range: 279 - 293

Received: Mar 16, 2016

Accepted: Aug 22, 2016

DOI: https://doi.org/10.1515/acve-2016-0025

Keywords
laboratory animals, outbtred, Swiss mice, IgG2c

© 2016 Živković Irena et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Characterization of Intor:Swiss Albino Mice Adopted in the Institute of Virology, Vaccines and Sera – Torlak, Belgrade in the Early Twentieth Century

Published Online: Sep 29, 2016

Page range: 279 - 293

Received: Mar 16, 2016

Accepted: Aug 22, 2016

DOI: https://doi.org/10.1515/acve-2016-0025

Keywordslaboratory animals, outbtred, Swiss mice, IgG2c

© 2016 Živković Irena et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
laboratory animals, outbtred, Swiss mice, IgG2c