[1. N. Salamat-Miller, M. Chittchang and T. P. Johnston, The use of mucoadhesive polymers in buccal drug delivery, Adv. Drug Deliv. Rev.57 (2005) 1666–1691; DOI: 10.1016/j.addr.2005.07.003.10.1016/j.addr.2005.07.003]Search in Google Scholar
[2. R. A. Medve, J. Wang and R. Karim, Tramadol and acetaminophen tablets for dental pain, Anesth. Prog.48 (2001) 79–81.]Search in Google Scholar
[3. B. W. Morrison, S. Christensen, W. Yuan, J. Brown, S. Amlani and B. Seidenberg, Analgesic efficacy of the cyclooxygenase-2-specific inhibitor rofecoxib in post-dental surgery pain: a randomized, controlled trial, Clin. Ther.21 (1999) 943–953; DOI: 10.1016/S0149-2918(99)80016-2.10.1016/S0149-2918(99)80016-2]Search in Google Scholar
[4. J. M. Swegle and C. Logemann, Management of common opioid-induced adverse effects, Am. Fam. Physician74 (2006) 1347–1354.]Search in Google Scholar
[5. I. Bjarnason, J. Hayllar, A. J. Macpherson and A. Russell, Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans, Gastroenterology104 (1993) 1832–1847.10.1016/0016-5085(93)90667-2]Search in Google Scholar
[6. A. Sultan, H. J. McQuay, R. A. Moore and S. Derry, Single dose oral flurbiprofen for acute postoperative pain in adults, Cochrane Libr. (2009); DOI: 10.1002/14651858.CD007358.10.1002/14651858.CD007358]Search in Google Scholar
[7. M. Takada, M. Fukusaki, Y. Terao, K. Yamashita, C. Inadomi, M. Takada and K. Sumikawa, Preadministration of flurbiprofen suppresses prostaglandin production and postoperative pain in orthopedic patients undergoing tourniquet inflation, J. Clin. Anesth.19 (2007) 97–100; DOI: 10.1016/j.jclinane.2006.05.028.10.1016/j.jclinane.2006.05.028]Search in Google Scholar
[8. R. K. Flath, M. L. Hicks, R. A. Dionne and G. B. Pelleu Jr., Pain suppression after pulpectomy with preoperative flurbiprofen, J. Endodont.13 (1987) 339–347; DOI: 10.1016/S0099-2399(87)80116-487.]Search in Google Scholar
[9. Y. Fujii and Y. Shiga, Flurbiprofen axetil preceded by venous occlusion in the prevention of pain on propofol injection in the hand: a prospective, randomized, double-blind, vehicle-controlled, dose-finding study in Japanese adult surgical patients, Clin. Ther.27 (2005) 588–593; 10.1016/j.clinthera.2005.05.003.]Search in Google Scholar
[10. P.-L. Lin, S.-Z. Fan, C.-H. Huang, H.-H. Huang, M.-C. Tsai, C.-J. Lin and W.-Z. Sun, Analgesic effect of lidocaine patch 5 % in the treatment of acute herpes zoster: a double-blind and vehicle-controlled study, Region. Anesth. Pain M.33 (2008) 320–325.]Search in Google Scholar
[11. L. Perioli, V. Ambrogi, S. Giovagnoli, M. Ricci, P. Blasi and C. Rossi, Mucoadhesive bilayered tablets for buccal sustained release of flurbiprofen, AAPS PharmSciTech.8 (2007) E20-E27; DOI: 10.1208/pt0803054.10.1208/pt0803054]Search in Google Scholar
[12. H. Okamoto, H. Taguchi, K. Iida and K. Danjo, Development of polymer film dosage forms of lidocaine for buccal administration: I. Penetration rate and release rate, J. Control. Release77 (2001) 253–260; DOI: 10.1016/s0168-3659(01)00509-001.]Search in Google Scholar
[13. Y. Sudhakar, K. Kuotsu and A. Bandyopadhyay, Buccal bioadhesive drug delivery—a promising option for orally less efficient drugs, J. Control. Release114 (2006) 15–40; 10.1016/j.jconrel.2006.04.012.10.1016/j.jconrel.2006.04.012]Search in Google Scholar
[14. V. F. Patel, F. Liu and M. B. Brown, Advances in oral transmucosal drug delivery, J. Control. Release153 (2011) 106–116; DOI: 10.1016/j.jconrel.2011.01.027.10.1016/j.jconrel.2011.01.027]Search in Google Scholar
[15. A. Bernkop-Schnürch and S. Steininger, Synthesis and characterisation of mucoadhesive thiolated polymers, Int. J. Pharm.194 (2000) 239–247; 10.1016/s0378-5173(99)00387-799.10.1016/S0378-5173(99)00387-7]Search in Google Scholar
[16. I. Knight, The development and applications of sucralose, a new high-intensity sweetener, Can. J. Physiol. Pharmacol.72 (1994) 435–439; DOI: 10.1139/y94-063.10.1139/y94-0637922876]Search in Google Scholar
[17. L. Allen, Featured excipient: capsule and tablet diluents, Int. J. Pharm. Compd.4 (2000) 306–312.]Search in Google Scholar
[18. V. M. Patel, B. G. Prajapati, H. V. Patel and K. M. Patel, Mucoadhesive bilayer tablets of propranolol hydrochloride, AAPS PharmSciTech. 8 (2007) E203-E208; 10.1208/pt0803077.]Search in Google Scholar
[19. L. Perioli, V. Ambrogi, D. Rubini, S. Giovagnoli, M. Ricci, P. Blasi and C. Rossi, Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease, J. Control. Release95 (2004) 521–533; DOI: 10.1016/j.jconrel.2003.12.018.10.1016/j.jconrel.2003.12.01815023463]Search in Google Scholar
[20. S. Mohammadi-Samani, R. Bahri-Najafi and G. Yousefi, Formulation and in vitro evaluation of prednisolone buccoadhesive tablets, Farmaco60 (2005) 339–344; DOI: 10.1016/j.farmac.2005.01.009.10.1016/j.farmac.2005.01.00915848210]Search in Google Scholar
[21. S. Edavalath and B. Rao, Design, development and optimization of buccal bioadhesive tablets of diclofenac sodium for the treatment of odontalgia, Ars Pharm.52 (2011) 5–13.]Search in Google Scholar
[22. M. S. Pendekal Ars Pharm P. K. Tegginamat, Formulation and evaluation of a bioadhesive patch for buccal delivery of tizanidine, Acta Pharm. Sin. B2 (2012) 318–324; DOI: 10.1016/j.apsb.2011.12.012.10.1016/j.apsb.2011.12.012]Search in Google Scholar
[23. N. Shah, G. Zhang, V. Apelian, F. Zeng, M. H. Infeld and A. W. Malick, Prediction of drug release from hydroxypropyl methylcellulose (HPMC) matrices: effect of polymer concentration, Pharm. Res.10 (1993) 1693–1695; DOI: 10.1023/a:1018901509855.10.1023/A:1018901509855]Search in Google Scholar
[24. J. Malakar, A. K. Nayak and S. Goswami, Use of response surface methodology in the formulation and optimization of bisoprolol fumarate matrix tablets for sustained drug release, ISRN Pharmaceutics 2012 (2012), article ID 730624; DOI: 10.5402/2012/730624.10.5402/2012/730624352986723378933]Search in Google Scholar
[25. S. Dash, P. N. Murthy, L. Nath and P. Chowdhury, Kinetic modeling on drug release from controlled drug delivery systems, Acta Pol. Pharm.67 (2010) 217–223; DOI: 10.1080/10717540490265379.10.1080/1071754049026537915168793]Search in Google Scholar
[26. D. Jones, Pharmaceutical Applications of Polymers for Drug Delivery, Smithers Rapra Publishing, U.K. 2004. pp. 31–35.]Search in Google Scholar
[27. J. Parojčić, Z. Ðurić, M. Jovanović and S. Ibrić, An investigation into the factors influencing drug release from hydrophilic matrix tablets based on novel carbomer polymers, Drug Deliv.11 (2004) 59–65.10.1080/10717540490265379]Search in Google Scholar
[28. X. Huang and C. S. Brazel, On the importance and mechanisms of burst release in matrix-controlled drug delivery systems, J. Control. Release73 (2001) 121–136; DOI: 10.1016/s0168-3659(01)00248-601.]Search in Google Scholar