<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Newly introduced methods of assaying simultaneously copper and zinc and zinc alone in serum by flame atomic-absorption spectrometry are simple and economical, especially in saving the consumption of serum material. Along with biochemical parameters, they have been successfully applied to diagnostics/prognostics of tuberculosis in children, through analyses of sera from pediatric patients with lung tuberculosis or suspected tuberculosis, enabling the follow-up of therapeutic efficiency. The prognostic strength of Cu and Cu/Zn ratio together with C-reactive protein, complement components C3 and C4, and erythrocyte sedimentation rate have been documented.</p></abstract>

Newly introduced methods of assaying simultaneously copper and zinc and zinc alone in serum by flame atomic-absorption spectrometry are simple and economical, especially in saving the consumption of serum material. Along with biochemical parameters, they have been successfully applied to diagnostics/prognostics of tuberculosis in children, through analyses of sera from pediatric patients with lung tuberculosis or suspected tuberculosis, enabling the follow-up of therapeutic efficiency. The prognostic strength of Cu and Cu/Zn ratio together with C-reactive protein, complement components C3 and C4, and erythrocyte sedimentation rate have been documented.

Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum

Faculty of Pharmacy and Biochemistry, University of Zagreb, HR-10000 Zagreb, Croatia

Agency for Medicinal Products and Medical Devices, HR-10000 Zagreb, Croatia

Srebrnjak Children’s Hospital, HR-10000 Zagreb, Croatia

Acta Pharmaceutica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Newly introduced methods of assaying simultaneously copper and zinc and zinc alone in serum by flame atomic-absorption spectrometry are simple and economical,...

Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum

Published Online: Sep 30, 2015

Page range: 321 - 329

Accepted: Jun 15, 2015

DOI: https://doi.org/10.1515/acph-2015-0027

Keywords
copper, zinc, Cu/Zn ratio, biochemical parameters, children’s serum, lung tuberculosis

© Svjetlana Luterotti et al.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum

Published Online: Sep 30, 2015

Page range: 321 - 329

Accepted: Jun 15, 2015

DOI: https://doi.org/10.1515/acph-2015-0027

Keywordscopper, zinc, Cu/Zn ratio, biochemical parameters, children’s serum, lung tuberculosis

© Svjetlana Luterotti et al.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
copper, zinc, Cu/Zn ratio, biochemical parameters, children’s serum, lung tuberculosis