<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_abm-2018-0005_s_005_w2aab3b7b4b1b6b1aab1c16b1Aa"><h3>Background</h3><p>The Migraine-Specific Quality of Life Questionnaire version 2.1 (MSQv2.1) is used to evaluate the impact of symptoms on the quality of life (QoL) of migraineurs.</p></sec><sec id="j_abm-2018-0005_s_006_w2aab3b7b4b1b6b1aab1c16b2Aa"><h3>Objective</h3><p>To evaluate primarily the concurrent validity, test–retest reliability, and internal consistency, and secondarily the sensitivity to change of a Thai version of the MSQv2.1.</p></sec><sec id="j_abm-2018-0005_s_007_w2aab3b7b4b1b6b1aab1c16b3Aa"><h3>Methods</h3><p>The original English version of the MSQv2.1 was translated into a Thai version. The Thai version of the MSQv2.1 was assessed for content and language equivalence. Validity of the Thai version of the MSQv2.1 was assessed using migraine characteristics in a prospective study conducted at the Chulalongkorn Comprehensive Headache Centre of King Chulalongkorn Memorial Hospital. Test–retest reliability and internal consistency were tested in migraineurs. Sensitivity to change was evaluated in another group of migraineurs using an 8-week follow-up.</p></sec><sec id="j_abm-2018-0005_s_008_w2aab3b7b4b1b6b1aab1c16b4Aa"><h3>Results</h3><p>We recruited 30 migraineurs to test the validity, test–retest reliability, and internal consistency of the Thai version of the MSQv2.1 and 11 migraineurs to test its sensitivity to change. The Thai version of the MSQv2.1 scores were significantly correlated with migraine symptoms (inverse coefficient range from –0.62 to –0.39) except for associated symptoms, which had no correlation with any of the dimensions or overall QoL score. Spearman’s correlation coefficient for test–retest reliability was 0.56–0.83, and Cronbach’s α for internal consistency was 0.91–0.96. Headache, including average pain duration per attack, pain severity score (numeric rating scale), associated symptoms and dimensions, and overall QoL score of the Thai version of MSQv2.1 improved over time (<italic>P</italic> &lt; 0.05). Moreover, improvement in headache correlated (coefficient range 0.67–0.77) with improvement in overall QoL score and some dimensions of the Thai version of the MSQv2.1 (coefficient range 0.66–0.77).</p></sec><sec id="j_abm-2018-0005_s_009_w2aab3b7b4b1b6b1aab1c16b5Aa"><h3>Conclusion</h3><p>The Thai version of the MSQv2.1 had validity, acceptable internal consistency, moderate-to-strong test–retest reliability, and strong correlation between improvement in headache severity and overall QoL score. A future study with a larger sample size and longer follow-up is required for better estimates of internal consistency and sensitivity to change.</p></sec></abstract>

BackgroundThe Migraine-Specific Quality of Life Questionnaire version 2.1 (MSQv2.1) is used to evaluate the impact of symptoms on the quality of life (QoL) of migraineurs.ObjectiveTo evaluate primarily the concurrent validity, test–retest reliability, and internal consistency, and secondarily the sensitivity to change of a Thai version of the MSQv2.1.MethodsThe original English version of the MSQv2.1 was translated into a Thai version. The Thai version of the MSQv2.1 was assessed for content and language equivalence. Validity of the Thai version of the MSQv2.1 was assessed using migraine characteristics in a prospective study conducted at the Chulalongkorn Comprehensive Headache Centre of King Chulalongkorn Memorial Hospital. Test–retest reliability and internal consistency were tested in migraineurs. Sensitivity to change was evaluated in another group of migraineurs using an 8-week follow-up.ResultsWe recruited 30 migraineurs to test the validity, test–retest reliability, and internal consistency of the Thai version of the MSQv2.1 and 11 migraineurs to test its sensitivity to change. The Thai version of the MSQv2.1 scores were significantly correlated with migraine symptoms (inverse coefficient range from –0.62 to –0.39) except for associated symptoms, which had no correlation with any of the dimensions or overall QoL score. Spearman’s correlation coefficient for test–retest reliability was 0.56–0.83, and Cronbach’s α for internal consistency was 0.91–0.96. Headache, including average pain duration per attack, pain severity score (numeric rating scale), associated symptoms and dimensions, and overall QoL score of the Thai version of MSQv2.1 improved over time (P < 0.05). Moreover, improvement in headache correlated (coefficient range 0.67–0.77) with improvement in overall QoL score and some dimensions of the Thai version of the MSQv2.1 (coefficient range 0.66–0.77).ConclusionThe Thai version of the MSQv2.1 had validity, acceptable internal consistency, moderate-to-strong test–retest reliability, and strong correlation between improvement in headache severity and overall QoL score. A future study with a larger sample size and longer follow-up is required for better estimates of internal consistency and sensitivity to change.

Validity, reliability, and sensitivity to change of the Thai version of the Migraine-Specific Quality of Life Questionnaire version 2.1

Department of Medicine, Faculty of Medicine, King Chulalongkorn Memorial Hospital

Asian Biomedicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

BackgroundThe Migraine-Specific Quality of Life Questionnaire version 2.1 (MSQv2.1) is used to evaluate the impact of symptoms on the quality of life (QoL) of...

Validity, reliability, and sensitivity to change of the Thai version of the Migraine-Specific Quality of Life Questionnaire version 2.1

Article Category: Original article

Published Online: Mar 21, 2018

Page range: 331 - 342

DOI: https://doi.org/10.1515/abm-2018-0005

Keywords
health-related quality of life, Migraine-Specific Quality of Life Questionnaire version 2.1, reliability, sensitivity to change, Thai version of the MSQv2.1, validity

© 2017 Thanin Asawavichienjinda, Pongpat Vorasayan, Jirawadee Noiwattanakul, Kammant Phanthumchinda

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Validity, reliability, and sensitivity to change of the Thai version of the Migraine-Specific Quality of Life Questionnaire version 2.1

Article Category: Original article

Published Online: Mar 21, 2018

Page range: 331 - 342

DOI: https://doi.org/10.1515/abm-2018-0005

Keywordshealth-related quality of life, Migraine-Specific Quality of Life Questionnaire version 2.1, reliability, sensitivity to change, Thai version of the MSQv2.1, validity

© 2017 Thanin Asawavichienjinda, Pongpat Vorasayan, Jirawadee Noiwattanakul, Kammant Phanthumchinda

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
health-related quality of life, Migraine-Specific Quality of Life Questionnaire version 2.1, reliability, sensitivity to change, Thai version of the MSQv2.1, validity