<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Leishmaniosis caused by Leishmania infantum is vector-born severe enzootic disease in dogs. It includes a wide spectrum of clinical symptoms, but the most characteristic are alterations in the hematopoetic system and renal failure. Also, infected animals could be asymptomatic, so the manifestation of L. infantum infection depends on many factors, including host’s immunological status. The aim of this survey was to find parameters related with hematopoetic and renal failure (hematology, biochemical parameters - urea, creatinine, serum proteins) in symptomatic and asymptomatic dogs seropositive for canine leishmaniosis. Within the hematological parameters, we found significant differences between symptomatic and asymptomatic dogs in the erythrogram and platelet count, but not in the leukogram. Significant differences between the two groups were found also for urea, creatinine, serum albumin and globulin, but not in serum total protein and A/G ratio. These findings indicate individual variability of the host’s response to infection with L. infantum.</p></abstract>

Leishmaniosis caused by Leishmania infantum is vector-born severe enzootic disease in dogs. It includes a wide spectrum of clinical symptoms, but the most characteristic are alterations in the hematopoetic system and renal failure. Also, infected animals could be asymptomatic, so the manifestation of L. infantum infection depends on many factors, including host’s immunological status. The aim of this survey was to find parameters related with hematopoetic and renal failure (hematology, biochemical parameters - urea, creatinine, serum proteins) in symptomatic and asymptomatic dogs seropositive for canine leishmaniosis. Within the hematological parameters, we found significant differences between symptomatic and asymptomatic dogs in the erythrogram and platelet count, but not in the leukogram. Significant differences between the two groups were found also for urea, creatinine, serum albumin and globulin, but not in serum total protein and A/G ratio. These findings indicate individual variability of the host’s response to infection with L. infantum.

Hematological and Biochemical Parameters in Symptomatic and Asymptomatic Leishmania-Seropositive Dogs

Department of Pathophysiology, Faculty of Veterinary Medicine – Skopje, Ss Cyril and Methodius University, Skopje

Department of Parasitology, Faculty of Veterinary Medicine – Skopje, Ss Cyril and Methodius University, Skopje

Macedonian Veterinary Review

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Leishmaniosis caused by Leishmania infantum is vector-born severe enzootic disease in dogs. It includes a wide spectrum of clinical symptoms, but the most...

Hematological and Biochemical Parameters in Symptomatic and Asymptomatic Leishmania-Seropositive Dogs

Published Online: Nov 18, 2015

Page range: 175 - 182

Received: Apr 16, 2015

Accepted: May 28, 2015

DOI: https://doi.org/10.14432/j.macvetrev.2015.06.04

Keywords
leishmaniosis, dog, hematology, biochemistry

© 2015

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Hematological and Biochemical Parameters in Symptomatic and Asymptomatic Leishmania-Seropositive Dogs

Published Online: Nov 18, 2015

Page range: 175 - 182

Received: Apr 16, 2015

Accepted: May 28, 2015

DOI: https://doi.org/10.14432/j.macvetrev.2015.06.04

Keywordsleishmaniosis, dog, hematology, biochemistry

© 2015

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
leishmaniosis, dog, hematology, biochemistry