<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Myxofibrosarcoma or myxoid malignant fibrous histiocytoma is one of the most common sarcomas of the limb. It is usually treated multimodally. Most frequent sites of metastasis are the bone, lung and lymph nodes. The present paper is a case report of a 65-year-old male with myxofibrosarcoma of the fibularis longus muscle, for which he first underwent surgery - tumor resection with appropriate margins. The tumor was staged pT2b cN0 cM0. Postoperative PET-CT revealed metabolically inactive pulmonary nodules. Two months after surgery, he underwent adjuvant radiotherapy, a total dose of 60 Gy and 6 courses of chemotherapy (doxorubicin and ifosfamide). Pulmonary nodules have been stationary on all subsequent imagistic studies. He is free of recurrence on long-term follow-up.</p></abstract>

Myxofibrosarcoma or myxoid malignant fibrous histiocytoma is one of the most common sarcomas of the limb. It is usually treated multimodally. Most frequent sites of metastasis are the bone, lung and lymph nodes. The present paper is a case report of a 65-year-old male with myxofibrosarcoma of the fibularis longus muscle, for which he first underwent surgery - tumor resection with appropriate margins. The tumor was staged pT2b cN0 cM0. Postoperative PET-CT revealed metabolically inactive pulmonary nodules. Two months after surgery, he underwent adjuvant radiotherapy, a total dose of 60 Gy and 6 courses of chemotherapy (doxorubicin and ifosfamide). Pulmonary nodules have been stationary on all subsequent imagistic studies. He is free of recurrence on long-term follow-up.

Positive outcome in a high-grade myxofibrosarcoma: a case report

Clinic of Medical Oncology, “Elias” University Emergency Hospital

“Carol Davila” University of Medicine and Pharmacy

Romanian Journal of Orthopaedic Surgery and Traumatology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Positive outcome in a high-grade myxofibrosarcoma: a case report"}

Myxofibrosarcoma or myxoid malignant fibrous histiocytoma is one of the most common sarcomas of the limb. It is usually treated multimodally. Most frequent...

Positive outcome in a high-grade myxofibrosarcoma: a case report

Published Online: Apr 26, 2018

Page range: 27 - 30

DOI: https://doi.org/10.2478/rojost-2018-0007

Keywords
limb sarcoma, radiotherapy, chemotherapy

© 2018 Mihaela Olaru et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Positive outcome in a high-grade myxofibrosarcoma: a case report

Published Online: Apr 26, 2018

Page range: 27 - 30

DOI: https://doi.org/10.2478/rojost-2018-0007

Keywordslimb sarcoma, radiotherapy, chemotherapy

© 2018 Mihaela Olaru et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
limb sarcoma, radiotherapy, chemotherapy