<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Staphylococcal toxic shock syndrome (TSS) is most frequently produced by TSS toxin-1 (TSST-1) and Staphylococcal enterotoxin B (SEB), and only rarely by enterotoxins A, C, D, E, and H. Various clinical pictures can occur depending on severity, patient age and immune status of the host. Severe forms, complicated by sepsis, are associated with a death rate of 50-60%. The case of a Caucasian female infant, aged seven weeks, hospitalized with a diffuse skin rash, characterized as allergodermia, who initially developed TSS with axillary intertrigo, is reported.</p><p>TSS was confirmed according to 2011 CDC criteria, and blood cultures positive for Methicillin-sensitive Staphylococcus aureus (MSSA). Severe development occurred initial, including acidosis, consumption coagulopathy, multiple organ failures (MOF), including impaired liver and kidney function. Central nervous system damage was manifest by seizures. Clinical management included medical supervision by a multidisciplinary team of infectious diseases specialist and intensive care specialist, as well as the initiation of a complex treatment plan to correct hydro electrolytic imbalances and acidosis. This treatment included antibiotic and antifungal therapy, diuretic therapy, immunoglobulins, and local treatment similar to a patient with burns to prevent superinfection of skin and mucous membranes lesions. There was a favourable response to the treatment with resolution of the illness.</p></abstract>

Staphylococcal toxic shock syndrome (TSS) is most frequently produced by TSS toxin-1 (TSST-1) and Staphylococcal enterotoxin B (SEB), and only rarely by enterotoxins A, C, D, E, and H. Various clinical pictures can occur depending on severity, patient age and immune status of the host. Severe forms, complicated by sepsis, are associated with a death rate of 50-60%. The case of a Caucasian female infant, aged seven weeks, hospitalized with a diffuse skin rash, characterized as allergodermia, who initially developed TSS with axillary intertrigo, is reported.TSS was confirmed according to 2011 CDC criteria, and blood cultures positive for Methicillin-sensitive Staphylococcus aureus (MSSA). Severe development occurred initial, including acidosis, consumption coagulopathy, multiple organ failures (MOF), including impaired liver and kidney function. Central nervous system damage was manifest by seizures. Clinical management included medical supervision by a multidisciplinary team of infectious diseases specialist and intensive care specialist, as well as the initiation of a complex treatment plan to correct hydro electrolytic imbalances and acidosis. This treatment included antibiotic and antifungal therapy, diuretic therapy, immunoglobulins, and local treatment similar to a patient with burns to prevent superinfection of skin and mucous membranes lesions. There was a favourable response to the treatment with resolution of the illness.

The Management of Staphylococcal Toxic Shock Syndrome. A Case Report

Lucian Blaga University of Sibiu, Faculty of Medicine, Sibiu, Romania

Sibiu County Clinical Emergency Hospital, Infectious Diseases Department, Sibiu, Romania

Pediatric Clinical Hospital Sibiu, Infectious Diseases Department, Sibiu, Romania

Pediatric Clinical Hospital Sibiu, Intensive Care Department, Sibiu, Romania

Foişor Clinical Hospital of Orthopedics, Traumatology and Osteoarticular Tuberculosis, Bucharest, Romania

The Journal of Critical Care Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"The Management of Staphylococcal Toxic Shock Syndrome. A Case Report"}

Staphylococcal toxic shock syndrome (TSS) is most frequently produced by TSS toxin-1 (TSST-1) and Staphylococcal enterotoxin B (SEB), and only rarely by...

The Management of Staphylococcal Toxic Shock Syndrome. A Case Report

Published Online: May 09, 2016

Page range: 85 - 88

Received: Feb 02, 2016

Accepted: Apr 05, 2016

DOI: https://doi.org/10.1515/jccm-2016-0011

Keywords
Staphylococcal toxic shock syndrome, TSS, management

© 2016 Victoria Bîrluţiu et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The Management of Staphylococcal Toxic Shock Syndrome. A Case Report

Published Online: May 09, 2016

Page range: 85 - 88

Received: Feb 02, 2016

Accepted: Apr 05, 2016

DOI: https://doi.org/10.1515/jccm-2016-0011

KeywordsStaphylococcal toxic shock syndrome, TSS, management

© 2016 Victoria Bîrluţiu et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Staphylococcal toxic shock syndrome, TSS, management