This article concerns the problem of assessing selected body compo- sition parameters after completion of antitumor therapy and comparing them with the same parameters of healthy children. A high percentage of overweight and obesity, as well as abnormal fat distribution in convalescents with cancer shows a significant adverse effect of therapy on body composition and suggests the need for early intervention in terms of diet and exercise, which would help patients to quickly achieve the proper parameters of body composition. Two main problems will be mentioned during the presented data analysis. Firstly, in each group there was a small number of observations. Because of this, the real differences between examined subgroups may have been omitted. Secondarily, many variables are correlated and are not normally distributed. Therefore, be- side the standard statistical tests to compare two groups, principal component analysis was applied to reduce the dimensions of the attribute space and to attempt to classify two groups of patients.
If the inline PDF is not rendering correctly, you can download the PDF file here.
Bjorge T. Engeland A. Tretli S. & Weiderpass E. (2007). Body size in relation to cancer of the uterine corpus in 1 million Norwegian women. Int J Cancer 15 120(2) 378-83.
Dai Z. Xu Y. C. & Niu L. (2007). Obesity and colorectal cancer risk: A meta- analysis of cohort studies. World J Gastroenterol 13(31) 4199-4206.
Foxhall L. E. (2013). The obesity-cancer connection and what we can do about it. Retrieved from American Cancer Society website: http://www.cancer.org/cancer/news/expertvoices/post/2013/02/28/the-obesity-cancer-connection-and-what-we-can-do-about-it.aspx.
Kubo A. & Corley D. A. (2006). Body Mass Index and Adenocarcinomas of the Esophagus or Gastric Cardia: A Systematic Review and Meta-analysis. Cancer Epidemiol Biomarkers Prev 15(5) 872-878.
Leiba A. Kark J. D. Afek A. Levi Z. Barchana M. Tzur D. Derazne E. et al. (2012). Overweight in Adolescence Is Related to Increased Risk of Future Urothelial Cancer Obesity 20(12) 2445-2450.
Merry A. H. Schouten L. J. Goldbohm R. A. & van den Brandt P. A. (2007). Body Mass Index height and risk of adenocarcinoma of the oesophagus and gastric cardia: a prospective cohort study. Gut 56(11) 1503-11.
Pischon T. Lahmann P. H. Boeing H. Friedenreich C. Norat T. Tjon- neland A. Halkjaer J. et al. (2006). Body size and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC). J Natl Cancer Inst 98(13) 920-931.
Reeves G. K. Pirie K. Beral V. Green J. Spencer E. & Bull D. (2007). Cancer incidence and mortality in relation to body mass index in the MillionWomen Study: cohort study. BMJ 335(7630) 1134.
Tirosh A. Shai I. Afek A. Dubnov-Raz G. Ayalon N. Gordon B. Derazne E. et al. (2011). Adolescent BMI trajectory and risk of diabetes versus coronary disease. N Engl J Med 364 1315-1325.