<abstract xmlns="http://www.w3.org/1999/xhtml"> Primary hyperhidrosis affects approximately 3% of the world’s population, particularly young female adults. It is defined as excessive, profuse sweating of the palms, soles, armpits and face. Conservative treament includes diverse modalities, however, surgical treatment has shown the best long-term results. The objective of this study was to assess some disease-specific epidemiological characteristics in a pre-selected group of patients seeking surgical therapy, as well as outcomes of thoracoscopic sympathectomy. The severity and impact of hypehidrosis was assessed, using Hyperhidrosis Disease Severity Scale (HDSS: patients rate the serverity of symptoms on a scale from 1 to 4). Thoracoscopic sympathectomy was performed using a double lumen endotracheal tube, via bilateral 5 mm dual port videothoracoscopic camera 0°, and an endoscopic ultrasound activated harmonic scalpel. The sympathetic chain was resected on both sides at the level of the second and the third thoracic ganglion (T2 and T3), using an ultrasound knife. The extirpated chain was also at the level T3-T4 and sent for <italic>ex tempore </italic>analysis<italic>. </italic>There were 162 patients undergoing thoracoscopic sympathectomy: 39.51% were males and 60.49% females; at presentation their mean age (± SD) was 30.5 (±8.3), range 16 - 58 years. Axillary hyperhidrosis occurs later than palmar-axillary-plantar (p&lt;0.05). A total of 35.18% of the evaluated patients were able to name at least one member of their families who also suffered from hyperhidrosis. The most commonly affected area was palmar-axillary-plantar (30.25%). Fifty patients (30.86%) received conservative therapy before surgery. The most commonly used conservative therapy modalities included different kinds of ointments/tinctures (11.73%), botox (8.02%) and iontophoresis (2.47%). Prior to surgery, 91.36% of patients reported severe sweating (HDSS score 3 or 4). The highest mean score was given for a combination of facial-palmar-axillaryplantar hyperhidrosis (3.80±0.24). All surgeries were successfully performed, with no complications, or perioperative morbidity. The mean hospital stay was 1.28±0.68 days long. After surgery, 93.21% of patients reported mild or moderate hyperhidrosis (HDSS score 1 or 2). Compensatory sweating (lower part of the back, and abdomen) was reported by 34.57% of patients after the surgery. All patients had a 6-months long follow-up: a significant improvement in quality of life was reported by 84.56% of patients (Yates corrected c2 (1) = 228.42; p=0.0000)); due to compensatory sweating, only 4.94% and 1.85% of patients reported bad and very bad quality of life, respectively. In conclusion, nowadays videothoracoscopic sympathectomy is a standard treatment for primary hyperhidrosis with a high success rate.</abstract>

Videothoracoscopic sympathectomy - a standard treatment for primary hyperhidrosis at the Clinic of Thoracic Surgery in Sremska Kamenica / Videotorakoskopska simpatektomija – standarna hirurška metoda za lečenje primarne hiperhidroze na Klinici za grudnu hirurgiju u Sremskoj Kamenici

<abstract xmlns="http://www.w3.org/1999/xhtml"> Vitiligo is an acquired, often hereditary skin depigmentation disorder, characterized by discrete, well-circumscribed, chalk-white macules or patches. It affects all age groups, but in more than half of the patients it occurs before the age of twenty, when self-image is being formed and social acceptance is of great importance. Although similar to the disease in adults, vitiligo in children and adolescents does have differences in epidemiology, association with other endocrine and/or autoimmune disorders, and treatment. This is a review of vitiligo in the pediatric population, emphasizing key differences with vitiligo in adults. According to the literature reports, we suggest that children and adolescents with vitiligo, especially non-segmental type, should perform annual screening for thyroid dysfunction, particularly for parameters of autoimmune thyroiditis.</abstract>

Institute of Child and Youth Health Care of Vojvodina, Novi Sad, Serbia

Clinic of Dermatovenereology Diseases, Clinical Center of Vojvodina, Novi Sad, Serbia

Vitiligo in Children and Adolescents: a Lliterature Review / Vitiligo kod dece i omladine - pregled literature

<abstract xmlns="http://www.w3.org/1999/xhtml"> Basal cell carcinoma (BCC) is the most common type of skin cancer in the Caucasian population. However, BCC of the genitalia is extremely rare. To the best of our knowledge, only 30 patients with BCC of the genitalia have been reported in the literature so far. BCC usually occurs in individuals over the age of 50, on sun-exposed areas of the body, and it is more prevalent in females. Superficial BCCs account for approximately 10% of BCC, and are commonly found on the trunk or limbs. This is a report on a 55-year-old male patient with penile BCC, and a literature review on this condition. The patient presented with asymptomatic skin lesions in the genital area which progressed during the last 15 years. Before admission, the patient received: antimycotics, antiviral, antibacterial and corticosteroid therapy, but without any improvement. Examination of the proximal penile skin revealed a sharply marked, smooth and shiny erythematous plaque of about 3.3 x 2 cm, with whitish squamae in the central zone. The histopathology finding revealed a superficial BCC and total excision was recommended. Treatment of the superficial BCC depends on its size and location. It includes surgical removal with possible reconstruction, radiotherapy, application of immunomodulators, local chemotherapy and local retinoid therapy. Although this is an extremely rare type of BCC, it is important to keep in mind that it may affect body areas seldom exposed to direct sunlight.</abstract>

Genital superficial basall cell carcinoma - a case report / Bazocelularni karcinom kože u genitalnoj regiji - prikaz slučaja

<abstract xmlns="http://www.w3.org/1999/xhtml"> The seven years’ war (1912 - 1918) and epidemics of infectious diseases, led to a great loss of lives and medical corps of Serbia. As already stated, venereal and skin diseases were spreading in the postwar period that can be seen from medical reports of dermatovenereology institutions. They contain appropriate pathologies and some specific conditions under which they developed<bold>. </bold>In dermatovenereal pathology, venereal diseases were still dominating. In the <italic>outpatient</italic><italic>Clinic for Skin and Venereal Diseases, </italic>10.000 patients were examined during the period from 1919 to 1921, venereal diseases accounted for 73.13%, whereas skin diseases accounted for 26.87% of all established diagnoses. A similar distribution existed at the territory of Serbia (Belgrade excluded) in 1931: venereal diseases accounted for 73.4%, and skin diseases for 26.6%; moreover, in Belgrade, the situation was even more drastic: venereal diseases accounted for 84.7%, and skin diseases for 15.3%. However, in the student population, the distribution was reversed: 43% and 57%, respectively. In regard to venereal diseases, in the series from 1919 to 1921, non-endemic syphilis was the most common disease, if serologically positive cases (latent syphilis) were added up to the clinically manifested cases. In the same series of patients, syphilis was staged as follows: syphilis I in 10%, syphilis II in 29.3%, syphilis III in 1.7%, tabes dorsalis in 0.8%, and latent syphilis in 56% of patients. In regions with endemic syphilis, from 1921 to 1925, the distribution was as follows: syphilis I in 4%, syphilis II in 49.8%, syphilis III in 18.3%, hereditary syphilis in 1.3%, and latent syphilis in 26.5% of patients. In patients suffering from gonorrhea, balanitis was found in 4.5%, and arthritis in 0.43% of cases. Generally, spreading of prostitution had a significant role, and its abolition was an important preventive action. In regard to skin diseases, in the above-mentioned series of patients, treated at the <italic>Outpatient Clinic for Skin and</italic><italic>Venereal Diseases </italic>(1919 - 1921), scabies was the commonest skin disease (26.7%), eczemas were the second most common (21.8%), followed by pyococcal diseases (20.4%), while fungal diseases (4.5%) and skin tuberculosis (1.9%) were considerably less frequent.This is the final report about the foundation of modern dermatovenereology in Serbia.</abstract>

Institute of Dermatology and Venereology, Clinical Center of Serbia, Belgrade, Serbia

History of dermatology and venereology in Serbia – part IV/3: Dermatovenereology in Serbia from 1919 – 1945, part 3 / Istorija dermatologije i venerologije u Srbiji - IV/1-3: Dermatovenerologija u Srbiji u periodu 1919 - 1945

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Serbian Journal of Dermatology and Venereology

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