Correlation Between Pulpal and Carotid Arteries Blood Flow in Two Age Groups

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Introduction Vascular network of dental pulp is supplied through common and external carotid artery and terminal dental branches that supply each pulp tissue. Age related changes of pulp tissue influence pulpal vascularization as well. The aim of this study was to compare and correlate pulpal and common and external carotid artery blood flow in young and middle age individuals of general population.

Material and Methods Two groups of 10 participants were included in the study, young (20-25 years) and middle age (50-55 years) group. Pulpal blood flow (PBF) measurements on intact right and left upper central incisors were performed using laser Doppler flowmetry (LDF) method. Carotid arteries blood flow was assessed using carotid ultrasonography.

Results PBF levels were significantly higher in young (3.11±0.67 and 3.46±1.11, right and left upper central incisors, respectively) compared to middle age (1.93±0.47 and 2.30±0.64, right and left upper central incisors, respectively) participants (independent sample t test; p<0.05). There was no correlation between common and external carotid artery blood flow and upper central incisors PBF in young as well as middle age participants, for right or left side.

Conclusion Absence of correlation between carotid arteries blood flow and PBF suggests that reduced PBF in middle age participants was probably not due to reduced blood supply from carotid arteries but it was result of age related changes at the level of pulpal blood vessels.

1. Tonder KJ. Blood flow and vascular pressure in the dental pulp. Summary. Acta Odontol Scand. 1980; 38:135-44. [DOI: 10.3109/00016358009004712] [PMID: 6998253]

2. Corpron RE, Avery JK, Lee SD. Ultrastructure of capillaries in the odontoblastic layer. J Dent Res. 1973; 52:393. [PMID: 8769670]

3. Yoshida S, Ohshima H. Distribution and organization of peripheral capillaries in dental pulp and their relationship to odontoblasts. Anat Rec. 1996; 245:313-26. [DOI: 10.1002/(SICI)1097-0185(199606)245:2<313::AIDAR14> 3.0.CO;2-S] [PMID: 8769670]

4. Olgart L. Neural control of pulpal blood flow. Crit Rev Oral Biol Med. 1996; 7:159-71. [PMID: 8875030]

5. Ahlquist M, Franzen O. Pulpal ischemia in man: effects on detection threshold, A-delta neural response and sharp dental pain. Endod Dent Traumatol. 1999; 15:6-16. [PMID: 10219148]

6. Solheim T. Amount of secondary dentin as an indicator of age. Scand J Dent Res. 1992; 100:193-9. [PMID: 1439521]

7. Ketterl W. Age-induced changes in the teeth and their attachment apparatus. Int Dent J. 1983; 33:262-71. [PMID: 6579031]

8. Saad AY. Regressive changes of the dental pulp complex in retained primary molars with congenitally missing successor teeth. J Clin Pediatr Dent. 1997; 22:63-7. [PMID: 9643208]

9. Taddei S, Virdis A, Ghiadoni L, Versari D, Salvetti A. Endothelium, aging, and hypertension. Curr Hypertens Rep. 2006; 8:84-9. [PMID: 16600164]

10. Greenwald SE. Ageing of the conduit arteries. J Pathol. 2007; 211:157-72. [DOI: 10.1002/path.2101] [PMID: 17200940]

11. O’Rourke MF. Arterial aging: pathophysiological principles. Vasc Med. 2007; 12:329-41. [DOI: 10.1177/1358863X07083392] [PMID: 18048471]

12. Sano Y, Ikawa M, Sugawara J, Horiuchi H, Mitani H. The effect of continuous intrusive force on human pulpal blood flow. Eur J Orthod. 2002; 24:159-66. [DOI: 10.1093/ejo/24.2.159] [PMID: 12001552]

13. Harada K, Sato M, Omura K. Blood-flow and neurosensory changes in the maxillary dental pulp after differing Le Fort I osteotomies. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004; 97:12-7. [DOI: 10.1016/j.tripleo.2003.08.028] [PMID: 14716251]

14. Emshoff R, Moschen I, Strobl H. Treatment outcomes of dental injury diagnoses as related to blood flow measurements from teeth. J Oral Rehabil. 2008; 35:209-17. [DOI: 10.1111/j.1365-2842.2007.01757.x] [PMID: 18254799]

15. Emshoff R, Emshoff I, Moschen I, Strobl H. Diagnostic characteristics of pulpal blood flow levels associated with adverse outcomes of luxated permanent maxillary incisors. Dent Traumatol. 2004; 20:270-5. [DOI: 10.1111/j.1600-9657.2004.00281.x] [PMID: 15355386]

16. Howard G, Sharrett AR, Heiss G, Evans GW, Chambless LE, Riley WA, et al. Carotid artery intimal-medial thickness distribution in general populations as evaluated by B-mode ultrasound. ARIC Investigators. Stroke. 1993; 24:1297-304. [PMID: 8362421]

17. Chu BC, Narita A, Aoki K, Yoshida T, Warabi T, Miyasaka K. Flow volume in the common carotid artery detected by color duplex sonography: an approach to the normal value and predictability of cerebral blood flow. Radiat Med. 2000; 18:239-44. [PMID: 11246999]

18. Soder PO, Soder B, Nowak J, Jogestrand T. Early carotid atherosclerosis in subjects with periodontal diseases. Stroke. 2005; 36:1195-200. [DOI: 10.1161/01.STR.0000165916.90593.cb] [PMID: 15879347]

19. Eigenbrodt ML, Bursac Z, Tracy RE, Mehta JL, Rose KM, Couper DJ. B-mode ultrasound common carotid artery intima-media thickness and external diameter: cross-sectional and longitudinal associations with carotid atherosclerosis in a large population sample. Cardiovasc Ultrasound. 2008; 6:10. [DOI: 10.1186/1476-7120-6-10] [PMID: 18321381]

20. Mattila KJ, Valtonen VV, Nieminen M, Huttunen JK. Dental infection and the risk of new coronary events: prospective study of patients with documented coronary artery disease. Clin Infect Dis. 1995; 20:588-92. [PMID: 7756480]

21. Joshipura KJ, Rimm EB, Douglass CW, Trichopoulos D, Ascherio A, Willett WC. Poor oral health and coronary heart disease. J Dent Res. 1996; 75:1631-6. [PMID: 8952614]

22. Loesche WJ, Schork A, Terpenning MS, Chen YM, Kerr C, Dominguez BL. The relationship between dental disease and cerebral vascular accident in elderly United States veterans. Ann Periodontol. 1998; 3:161-74. [PMID: 9722700]

23. Morrison HI, Ellison LF, Taylor GW. Periodontal disease and risk of fatal coronary heart and cerebrovascular diseases. J Cardiovasc Risk. 1999; 6:7-11. [PMID: 10197286]

24. Chiu B. Multiple infections in carotid atherosclerotic plaques. Am Heart J. 1999; 138:S534-6. [PMID: 10539867]

25. Offenbacher S, Madianos PN, Champagne CM, Southerland JH, Paquette DW, Williams RC, et al. Periodontitis-atherosclerosis syndrome: an expanded model of pathogenesis. J Periodontal Res. 1999; 34:346-52. [PMID: 10685359]

26. Haraszthy VI, Zambon JJ, Trevisan M, Zeid M, Genco RJ. Identification of periodontal pathogens in atheromatous plaques. J Periodontol. 2000; 71:1554-60. [PMID: 11063387]

27. Cairo F, Gaeta C, Dorigo W, Oggioni MR, Pratesi C, Pini Prato GP, et al. Periodontal pathogens in atheromatous plaques. A controlled clinical and laboratory trial. J Periodontal Res. 2004; 39:442-6. [DOI: 10.1111/j.1600-0765.2004.00761.x] [PMID: 15491349]

28. Schoning M, Walter J, Scheel P. Estimation of cerebral blood flow through color duplex sonography of the carotid and vertebral arteries in healthy adults. Stroke. 1994; 25:17-22. [PMID: 8266366]

29. Schoning M, Hartig B. Age dependence of total cerebral blood flow volume from childhood to adulthood. J Cereb Blood Flow Metab. 1996; 16:827-33. [PMID: 8784227]

30. Schoning M, Hartig B. The development of hemodynamics in the extracranial carotid and vertebral arteries. Ultrasound Med Biol. 1998; 24:655-62. [DOI: 10.1016/S0301-5629(98)00029-5] [PMID: 9695268]

31. Ikawa M, Komatsu H, Ikawa K, Mayanagi H, Shimauchi H. Age-related changes in the human pulpal blood flow measured by laser Doppler flowmetry. Dent Traumatol. 2003; 19:36-40. [DOI: 10.1034/j.1600-9657.2003.00120.x] [PMID: 12656853]

32. Bennett CG, Kelln EE, Biddington WR. Age changes of the vascular pattern of the human dental pulp. Arch Oral Biol. 1965; 10:995-8. [DOI: 10.1016/0003-9969(65)90093-2] [PMID: 5227002]

33. Bernick S. Age changes in the blood supply to human teeth. J Dent Res. 1967; 46:544-50. [DOI: 10.1177/00220345670460031501] [PMID: 5338250]

34. Espina AI, Castellanos AV, Fereira JL. Age-related changes in blood capillary endothelium of human dental pulp: an ultrastructural study. Int Endod J. 2003; 36:395-403. [DOI: 10.1046/j.1365-2591.2003.00659.x] [PMID: 12801286]

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