Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations
, , and | Aug 19, 2016
Published Online: Aug 19, 2016
Page range: 65 - 82
DOI: https://doi.org/10.1515/scjme-2016-0012
Keywords
© 2016 Peciar Peter et al., published by De Gruyter Open
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
This paper focuses on the characterization of the tabletting process and analysis one of the most common pharmaceutical excipients MCC Avicel PH102 by Heckel, Kawakita, Cooper-Eaton and Adams compaction equations. Experimental material was determined by measuring its parameters as particle size distribution, angle of wall friction and flow properties and for more detailed characteristics of the material particles, microscopy images of the powder before and after compressing were created.