Human Health Concenrs of the Metalworking Fluid Components

Part II – Biocides, corrosion inhibitors and neutralizing agents

Kristína Gerulová 1 , Eva Buranská 2 , and Maroš Soldán 1
  • 1 Institute of Integrated Safety, Slovak University of Technology in Bratislava, Faculty of Materials Science and Technology in Trnava, 917 24, Trnava
  • 2 Institute of Production Technologies, Slovak University of Technology in Bratislava, Faculty of Materials Science and Technology in Trnava, 917 24, Trnava


The exploration of 209 available Material safety data sheets of 85 straight oils, 46 emulsions, 51 semi-synthetics and 27 synthetics was carried out to provide a report on the most used components defined as dangerous substances. As many as 217 of different substances of which 15 were identified as biocides, 17 as corrosion inhibitors or neutralizing agent, 17 were lubricity improvers and 38 different base fluids, lubricity solvents or surfactants, while 93 substances were not identified specifically and 37 substances occurred only once. This article is focused on the list of biocides, neutralizing agents and corrosion inhibitors identified in all types of MWFs and their possible health effects.

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  • 1. CHENG, C., et al. 2005. Treatment of spent metalworking fluids. Water Res., Vol. 39, pp. 4051–4063.

  • 2. KEMP, C., P., HILL, I. 2004. Health and safety aspects in the live music industry, p. 298.

  • 3. PARK, D. 2012. The Occupational Exposure Limit for Fluid Aerosol Generated in Metalworking Operations: Limitations and Recommendations. Saf. Health Work, 3(1), p. 10.

  • 4. SCHWARZ, M. et al. 2015. Environmental and health aspects of metalworking fluid use. Polish J. Environ. Stud., 24(1), pp. 37–45.

  • 5. De GROOTE, M., A., HUITT, G. 2012. Infections due to rapidly growing mycobacteria. Clin. Infect. Dis., No. 42, pp. 1756–1763.

  • 6. FRIESEN, M., C., et al. 2012. Metalworking fluid exposure and cancer risk in a retrospective cohort of female autoworkers. Cancer Causes Control, 23(7), pp. 1075–82.

  • 7. van WENDEL, B., et al., 2005. An assessment of dermal exposure to semi-synthetic metal working fluids by different methods to group workers for an epidemiological study on dermatitis. Occup. Environ. Med., 62(9), pp. 633–41.

  • 8. LILLIENBERG, L., et al. 2010. Respiratory symptoms and exposure-response relations in workers exposed to metalworking fluid aerosols. Ann. Occup. Hyg., 54(4), pp. 403–11.

  • 9. SAHA, R., DONOFRIO, R., S. 2012. The microbiology of metalworking fluids. Appl. Microbiol. Biotechnol., 94(5), pp. 1119–1130.

  • 10. TRAFNY, E. 2013. Microorganisms in metalworking fluids: current issues in research and management. Int. J. Occup. Med. Environ. Health, 26(1), pp. 4–15.

  • 11. DILGER, S., et al. 2005. Bacterial contamination of preserved and non-preserved metal working fluids. Int. J. Hyg. Environ. Health, 208(6), pp. 467–76.

  • 12. LODDERS, N., KÄMPFER, P. 2012. A combined cultivation and cultivation-independent approach shows high bacterial diversity in water-miscible metalworking fluids. Syst. Appl. Microbiol., 35(4), pp. 246–252.

  • 13. RUDNICK, L., R. 2009. Lubricant Additives Chemistry and Applications. CRC Press Taylor & Francis Group LCC, 209 p.

  • 14. TRAFNY, E. A. et al. 2015. Microbial contamination and biofilms on machines of metal industry using metalworking fluids with or without biocides. Int. Biodeterior. Biodegradation, vol. 99, pp. 31–38.

  • 15. HUIZING, I., T., et al. 2011. Evaluation Manual for the Authorisation of plant protection products and biocides EU part Biocides Chapter 2 Physical and chemical properties Authors.

  • 16. BAKALOVA, S. 2008. Microbial toxicity of ethanolamines. Biotechnol. Biotechnol. Equip., 22(2), pp. 716–720.

  • 17. LOTIERZO, A. et al. 2016. Insight into the role of amines in Metal Working Fluids. Corros. Sci..

  • 18. Metal Working Fluids Recommendation for Chronic Inhalation Studies National Institute for Occupational Safety and Health. 2001. p. 90.

  • 19. MADAN, V., BECK, M., H. 2006. Occupational allergic contact dermatitis from N,N-methylene-bis-5-methyl-oxazolidine in coolant oils. Contact Dermatitis, 55(1), pp. 39–41.

  • 20. “ECHA - European chemicals agency.” [Online]. Available:

  • 21. GRAINGE, C., et al. 2013. Case series reporting the effectiveness of mycophenolate mofetil in treatmentresistant asthma. Eur. Respir. J., 42(4), pp. 1134–1137.

  • 22. Harmonised classification and labeling proposal for N,N’-methylene bismorpholine (MBM) - Lubrizol comments for the public consultation. 2016, pp. 1–26.

  • 23. OI, M. 2011. Emission scenario document on the use of metalworking fluids OECD Environment, Health and Safety Publications Series on Emission Scenario Documents Number 28, ENV/JM/MONO(2011)18, 33(28), pp. 1–127.

  • 24. BRUTTO, P., E. 2013. Amines 101 for Metalworking Fluids. Tribol. Lubr. Technol., pp. 2–3.

  • 25. JAGADEVAN, S., et al. 2013. Treatment of waste metalworking fluid by a hybrid ozone-biological process. J. Hazard. Mater., Vol. 244–245, pp. 394–402.

  • 26. FROSCH, P., J., et al. 2006. Contact Dermatitis. Springer Science & Business Media.

  • 27. Boric Acid and Metalworking Fluids. 2007. pp. 1–2.

  • 28. ECHA (European Chemicals Agency), “Member state committee draft support document for identification of boric acid as a substance of very high concern because of its CMR properties,” SVHC Support Doc., 2010. Vol. 2, pp. 1–27.

  • 29. PATNAIK, P. 2007. A Comprehensive Guide to the Hazardous Properties of Chemical Substances, 3rd ed.

  • 30. AMRITA, M., et al. 2014. Evaluation of Cutting Fluid With Nanoinclusions. J. Nanotechnol. Eng. Med., 4(3), pp. 1-11.


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