Secondary Bone Determinations in Choriocarcinoma

Gestational trophoblastic diseases represent a heterogeneous group of disorders that arise from trophoblastic epithelium. Choriocarcinoma is a highly anaplastic malignancy derived from trophoblastic cells. It is characterized by the secretion of human chorionic gonadotropin and early hematogenous metastasis. Metastatic choriocarcinoma in bones is very rare. Gestational trophoblastic diseases can follow normal pregnancy, ectopic pregnancy, abortions or molar pregnancy. However, the presence of bone metastases in a young woman at reproductive age requires systematic assessment for a primary lesion, for 1-2 years. This paper aims to present the bone sites where these metastases can occur, as well as the review of literature supported by a pictorial essay.