Literature review. Noninvasive fungal rhinosinusitis

Lucia Cojocari 1  and Alexandru Sandul 2 , 3
  • 1 Department of Otorhinolaryngology, “Nicolae Testemitanu” State University of Medicine and Pharmacy, Chisinau, 165 Stefan Cel Mare si Sfant Blvd., MD-2004, Chisinau, Moldova (Republic of)
  • 2 Department of Otorhinolaryngology, “Nicolae Testemitanu” State University of Medicine and Pharmacy, Chisinau, Republic of Moldova Moldova (Republic of)
  • 3 Department of Otorhinolaryngology, Republican Clinical Hospital, Chisinau, Moldova (Republic of)

Abstract

Fungus ball (FB) of the paranasal sinuses has a distinctive clinicopathological presentation. The disease occurs more frequently in elderly patients and has a female preponderance. Classically, it involves only one paranasal sinus in more than 90% of the cases, most commonly the maxillary sinus. Imaging characteristics (calcifications and / or erosion of the inner wall of the sinus visible on CT) and histopathological ones (luminal aggregation of fungal hyphae) confirm the diagnosis.

Allergic fungal rhinosinusitis (AFRS) usually occurs in younger, immunocompetent patients, with a history of atopy, including allergic rhinitis and / or asthma, or a long clinical picture of chronic rhinosinusitis (CRS), refractory to antibiotic treatment. Nasal polyps (NP) are present in almost all patients, while extra-sinusal complications are described only in some of them. Usually, there is involvement of several sinuses, as well as bilateral damage. The definitive diagnosis is confirmed only by examining surgical specimens - the characteristic appearance of eosinophilic mucin is the most reliable indicator of AFRS.

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  • 1. Mensi M., Salgarello S., Pinsi G., Piccioni M. - Mycetoma of the maxillary sinus: endodontic and microbiological correlations. Oral Surg Oral Med Oral Pathol Oral Radiol Endod., 2004;98(1):119-123.

  • 2. Chatterjee S.S., Chakrabarti A. - Epidemiology and Medical Mycology of Fungal Rhinosinusitis. Otorhinolaryngol Clin: An Int J, 2009;1(1):1-13.

  • 3. Aribandi M., McCoy V.A., Bazan C. 3rd - Imaging features of invasive and noninvasive fungal sinusitis: a review. Radiographics, 2007;27(5):1283-1296.

  • 4. Workshop on Fungal Sinusitis. http://www.isham.org/pdf/Report,%20fungal%20sinusitis%20workshop.pdf (vizitat 30.05.2016).

  • 5. Thompson G.R. 3rd, Patterson T.F. - Fungal disease of the nose and paranasal sinuses. J Allergy Clin Immunol., 2012;129(2):321-326. doi:

    • Crossref
    • Export Citation
  • 6. Patrascu E., Manea C., Sarafoleanu C. - Difficulties in the diagnosis of fungal rhinosinusitis -Literature review. Romanian Journal of Rhinology, 2016;6(21):11-17.

  • 7. Lop-Gros J., Gras-Cabrerizo J.R., Bothe-González C., Montserrat-Gili J.R., Sumarroca-Trouboul A., Massegur-Solench H. - Fungus ball of the paranasal sinuses: Analysis of our serie of patients. Acta Otorrinolaringol Esp., 2016;67(4):220-225.

  • 8. Zhu H., Zhang W., Guan J., Ye H., Su K. - CT imaging and clinical features of sinus fungus ball with bone erosion. J Nat Sci., 2015;1(4):e69.

  • 9. Bosi G.R., de Braga G.L., de Almeida T.S., de Carli S. - Fungus ball of the paranasal sinuses: Report of two cases and literature review. Int Arch Otorhinolaryngol., 2012;16(2):286-290.

  • 10. Chen J.C., Ho C.Y. - The significance of computed tomographic findings in the diagnosis of fungus ball in the paranasal sinuses. Am J Rhinol Allergy, 2012;26(2):117-119. doi:

    • Crossref
    • Export Citation
  • 11. Naik S.M., Ravishankar S., Deekshith R., et al. - Management of fungal sinusitis: A retrospective study in a medical college hospital. Online J Otolaryngol., 2015;5(3):39-47.

  • 12. Oshima H., Nomura K., Sugawara M., Arakawa K., Oshima T., Katori Y. - Septal deviation is associated with maxillary sinus fungus ball in male patients. Tohoku J Exp Med., 2014;232(3):201-206.

  • 13. Shin J.M., Baek B.J., Byun J.Y., Jun Y.J., Lee J.Y. - Analysis of sinonasal anatomical variations associated with maxillary sinus fungal balls. Auris Nasus Larynx, 2016;43(5):524-528. doi:

    • Crossref
    • Export Citation
  • 14. Fokkens W., Lund V., Mullol J., et al. - European Position Paper on Rhinosinusitis and Nasal Polyps 2012. Rhinology, 2012;50(Suppl 23):1-298.

  • 15. Baroody F.M., Naclerio R.M. - Immunology of the Upper Airway and Pathophysiology and Treatment of Allergic Rhinitis. In: Flint P.W., Haughey B.H., Lund V.J., Niparko J.K., Richardson M.A., Robbins K.T., Thomas J.R. (eds.) - Cummings Otolaryngology - Head and Neck Surgery. Fifth Edition. Philadelphia: Elsevier, 2010;p.597-623.

  • 16. Hamilos D.L. - Host-microbial interactions in patients with chronic rhinosinusitis. J Allergy Clin Immunol., 2014;133(3):640-653.e4. doi:

    • Crossref
    • Export Citation
  • 17. Stevens W.W., Lee R.J., Schleimer R.P., Cohen N.A. - Chronic rhinosinusitis pathogenesis. J Allergy Clin Immunol., 2015;136(6):1442-1453.

  • 18. Munkholm M., Mortensen J. - Mucociliary clearance: pathophysiological aspects. Clin Physiol Funct Imaging, 2014;34(3):171-177.

  • 19. Meltzer E.O., Hamilos D.L., Hadley J.A., et al. - Rhinosinusitis: establishing definitions for clinical research and patient care. J Allergy Clin Immunol., 2004;114(6 Suppl):155-212.

  • 20. Chakrabarti A., Kaur H. - Allergic Aspergillus Rhinosinusitis. J Fungi, 2016;2(32):1-29.

  • 21. Ponikau J.U., Sherris D.A., Kern E.B., et al. - The diagnosis and incidence of allergic fungal sinusitis. Mayo Clin Proc., 1999;74(9):877-884.

  • 22. Klossek J.M., Serrano E., Péloquin L., Percodani J., Fontanel J.P., Pessey J.J. - Functional endoscopic sinus surgery and 109 mycetomas of paranasal sinuses. Laryngoscope, 1997;107(1):112-117.

  • 23. deShazo R.D., O’Brien M., Chapin K., Soto-Aquilar M., Swain R., Lyons M., Bryars W.C. Jr, Alsip S. - Criteria for the diagnosis of sinus mycetoma. J Allergy Clin Immunol., 1997;99(4):475-485.

  • 24. Inci M., Ozkan F., Aksoy A., Kelles M. - Radiological aspect of fungus ball within a mucocele of the sphenoid sinus. JBR-BTR, 2013;96(6):372-374.

  • 25. Stephens J.C., Saleh H.A. - Evaluation and treatment of isolated maxillary sinus disease. Curr Opin Otolaryngol Head Neck Surg., 2013;21(1):50-57. doi:

    • Crossref
    • Export Citation
  • 26. Kim S.T., Choi J.H., Jeon H.G., Cha H.E., Hwang Y.J., Chung Y.S. - Comparison between polymerase chain reaction and fungal culture for the detection of fungi in patients with chronic sinusitis and normal controls. Acta Otolaryngol., 2005;125(1):72-75.

  • 27. Nicolai P., Lombardi D., Tomenzoli D., Villaret A.B., Piccioni M., Mensi M., Maroldi R. - Fungus ball of the paranasal sinuses: experience in 160 patients treated with endoscopic surgery. Laryngoscope, 2009;119(11):2275-2279. doi:

    • Crossref
    • Export Citation
  • 28. Pant H., Schembri M., Wormald P., Macardle P.J. - IgE-mediated fungal allergy in allergic fungal sinusitis. Laryngoscope, 2009;119(6):1046-1052. doi:

    • Crossref
    • Export Citation
  • 29. Laury A.M., Wise S.K. - Chapter 7: Allergic fungal rhinosinusitis. Am J Rhinol Allergy, 2013;27 Suppl 1:S26-27. doi:

    • Crossref
    • Export Citation
  • 30. Khattar V.S., Hathiram B.T. - Allergic Fungal Rhinosinusitis. Otorhinolaryngol Clin Int J, 2009;1(1):37-44.

  • 31. Daniller T. - Allergic Fungal Rhinosinusitis. Curr Allergy Clin Immunol., 2013;26(1):20-24.

  • 32. Ryan M.W. - Allergic fungal rhinosinusitis. Otolaryngol Clin North Am., 2011;44(3):697-710., ix-x. doi:

    • Crossref
    • Export Citation
  • 33. Corradini C., Del Ninno M., Schiavino D., Patriarca G., Paludetti G. - Allergic fungal sinusitis. A naso-sinusal specific hyperreactivity for an infectious disease? Acta Otorhinolaryngol Ital., 2003;23(3):168-174.

  • 34. Marple B.F. - Allergic fungal rhinosinusitis: current theories and management strategies. Laryngoscope, 2001;111(6):1006-1019.

  • 35. Marglani O. - Update in the management of allergic fungal sinusitis. Saudi Med J, 2014;35(8):791-795.

  • 36. Daudia A., Jones N. - Advances in management of paranasal sinus aspergillosis. J Laryngol Otol., 2008;122(4):331-335. Epub 2007 Oct 12.

  • 37. Shah N.J., Rathore A. - Intracranial Extension of Fungal Sinusitis. Otorhinolaryngology Clinics: An Internattional Journal, 2009;1(1):55-61.

  • 38. Chakrabarti A., Denning D., Ferguson B., et al. - Fungal rhinosinusitis: a categorization and definitional schema addressing current controversies. Laryngoscope, 2009;119(9):1809-1818. doi:

    • Crossref
    • Export Citation
  • 39. Ferguson B.J. - Eosinophilic mucin rhinosinusitis: a distinct clinicopathological entity. Laryngoscope, 2000;110(5 Pt 1):799-813.

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