Endoscopic sphenoid sinus surgery – gold standard approach or major risk technique?

<abstract xmlns="http://www.w3.org/1999/xhtml">Currently, the cases continue to develop due to the rapid spread of COVID-19 via human-to-human transmission. Because there are no definitive anti COVID-19 drugs or vaccines available to treat this fatal infection, supporting medication to relieve the patient’s manifestations is generally the only choice. Because of the homology of COVID-19 pandemic and the previous SARS coronavirus outbreak in epidemiology, genomics, pathogenesis, and the widespread use of herbal medicine for the previous SARS outbreak, clinical data suggesting the beneficial impact of herbal medicine in the treatment of COVID-19 infections is discussed. 3-Chymotrypsin-protease inhibition, blocking RNA-dependent RNA polymerase activity, inhibition of helicase protein, inhibition of replication, inhibition of viral cell entry and immunomodulatory effect are the scientific reported anti-coronavirus effects of herb-derived compounds. The findings of a number of clinical experiences have shown that herbal medicine plays an important role in the treatment of COVID-19, giving new hope for COVID-19 prevention and control.</abstract>

What is the efficacy of herbal medicine in the treatment of COVID-19 infection?

<abstract xmlns="http://www.w3.org/1999/xhtml">Fungus ball of the maxillary sinus (FBMS) is the most common form of chronic fungal rhinosinusitis in adults. It is a condition of old age, usually with unilateral involvement, and with female preponderance. It is especially described in immunocompetent individuals and is characterized by a slow and benign evolution. Although the etiology, pathogenesis and natural history of fungal rhino-sinusitis have been studied extensively, they are far from being fully understood. The clinical presentation and endoscopic findings in patients with fungus ball of the maxillary sinus are nonspecific, often identical to those of chronic bacterial rhinosinusitis and the cultures are often negative. Imaging evaluation by CT scan suggests, by characteristic signs, a correct diagnosis, which is then correlated with the histological identification of fungal hyphae. Microbiological, histopathological and mycological examinations of nasal secretion established with certainty a variety of bacteria (70%) and fungi (61.7%) in a group of 60 patients with FBMS included in a three-year study. The most commonly detected bacterial floras were <italic>Staphylococcus aureus, Citrobacter Koseri, Haemophilus influenzae, Pseudomonas aeruginosa, Moraxella catarrhalis</italic> and <italic>Klebsiella oxytoca</italic>. On culture media, the most common fungal agents were <italic>Aspergillus fumigatus</italic> and <italic>Aspergillus flavus.</italic></abstract>

Fungus ball of the maxillary sinus: clinical and diagnostic characteristics

<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>BACKGROUND.</bold> Starting from the European and American guidelines regarding sedation during gastrointestinal investigations and continuing with the American Society of Anesthesiologists (ASA) recommendations, we have developed a software that helps the ENT specialist to decide whether the patient can undergo a moderate sedation in the operating room, or in the outpatient office, during the drug-induced sleep endoscopy.<bold>MATERIAL AND METHODS.</bold> The application is written in C#, using the. NET Framework, and is available for the Windows operating system. The application has a very simple and user-friendly interface, and a bare-bones implementation, focusing strictly on the decision-making process.<bold>RESULTS</bold>. The application involves the information obtained from patient history, clinical examination and polysomnography. After filling all the patient’s data, it will show the result that can be one of the following: ”treatment can be ambulatory”, “treatment should be done in the hospital” or “treatment is not recommended”.<bold>CONCLUSION.</bold> The decision-making software application may substitute the evaluation of the anaesthesiologist during drug-induced sleep endoscopy in certain conditions.</abstract>

“Carol Davila” University of Medicine and Pharmacy

“Grigore T. Popa” University of Medicine and Pharmacy

Administration of anaesthesia during drug-induced sleep endoscopy: implementation of a computer system to assist the decision on how to administer analgosedation

<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>BACKGROUND.</bold> Nasal septum deviations are disorders in which the nasal septum has an abnormal conformation that affects nasal breathing. Surgical correction of the deviated nasal septum, performed by various techniques, is one of the methods of repermeabilization of the upper airway. The aim of the present study was to evaluate the efficacy of endoscopic surgical treatment of the nasal septum deviation on the nasal obstruction, as well as to evaluate the frequency of postoperative complications compared to classical septoplasty.<bold>MATERIAL AND METHODS.</bold> A retrospective longitudinal study was performed on a group of 92 patients diagnosed with nasal septal deviation, between 2014-2018. 32 patients were excluded from the study after the exclusion criteria were applied. Two groups of 30 patients each were formed: Group I, endoscopic septoplasty was performed; Group II, the conventional septoplasty was used. An objective endoscopic and rhinomanometric evaluation, as well as a subjective assessment of symptoms (nasal obstruction, headache, posterior rhinorrhea, sneezing), was performed preoperatively and at 3 months postoperatively.<bold>RESULTS.</bold> The study showed better results (p&lt;0.05) and fewer complications in endoscopic septoplasty compared to the traditional one, the endoscopic septoplasty providing better lighting and improved access, allowing a limited incision.<bold>CONCLUSION.</bold> Endoscopic septoplasty can be considered a reliable alternative to traditional techniques. It is essential to correctly identify the type of preoperative deformity in order to select the appropriate surgical strategy.</abstract>

“George Emil Palade” University of Medicine, Pharmacy, Science and Technology

Endoscopic versus conventional septoplasty in the treatment of obstructive nasal septal deviation

<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>BACKGROUND.</bold> Septoplasty is an age-old surgery performed mainly for a deviated nasal septum. Various methods have been described and the surgery is left to the choice of the surgeon. Traditional septoplasty has taken a back seat in the modern era because of various complications. Newer techniques are being practiced owing to better outcomes. Hydrodissection for septal flap elevation has been both criticized and appreciated because of multiple reasons. In this study, we have used this technique in practice and evaluated its outcome.<bold>MATERIAL AND METHODS.</bold> 184 patients with Deviated Nasal Septum (DNS) were evaluated. 82 in Group 1 underwent conventional septoplasty with Freer’s elevator and 102 in Group 2 underwent septoplasty with hydrodissection using Normal Saline (NS). Time taken to perform flap elevation, status of the mucoperichondrial flap intra-operatively and scoring of adhesions 4 weeks postoperatively were the parameters of study.<bold>RESULTS.</bold> 19 out of 82 cases had tears in the mucoperichondrium in Group 1, amounting to 23.17%. 11 patients out of 102 had tears in Group 2, amounting to 10.78%. The average time taken to perform the flap elevation was 11 minutes in Group 1 and 5 minutes in Group 2. Average score in crusting/adhesions was 0.66 in Group 1 and 0.53 in Group 2, out of a possible 4.<bold>CONCLUSION.</bold> Hydrodissection in septoplasty for the elevation of the mucoperichondrium and mucoperiosteum is a useful step in surgery provided that it is performed using Normal Saline. It is easy to perform, inexpensive and completely safe to perform without any serious complications.</abstract>

Role of hydrodissection in septoplasty: a modern outlook

<abstract xmlns="http://www.w3.org/1999/xhtml">Mucoceles are benign, expansive, cystic tumors, affecting especially the adult, with development in the paranasal sinuses. Clinical symptoms are not specific. These are rare conditions that originate within the sinusal mucosa, favoured by the obstruction of the sinus ostium. Due to the inflammation and the expansive character of the tumor, with the erosion of the bony walls, combined forms can develop, with the involvement of two or more sinuses, most frequently with fronto-ethmoidal localization.The authors carry out a clinical retrospective study on 25 cases of mucoceles of the paranasal sinuses, diagnosed and treated in the ENT Clinic of the “Sfantul Spiridon” Emergency Clinical Hospital Iasi, during 2015-2019. The authors insist on aspects related to clinical and radiological diagnosis (CT scanner), as well as surgical treatment by external approach.The postoperative evolution is generally simple, with full recovery, without complications or recurrences.The diagnosis of the mucoceles of the paranasal sinuses consists in radiologic techniques by preoperative CT scan examination, intraoperative macroscopic aspect and histopathological result.Surgical approach with complete excision of the tumor and creating a new sinusal drainage path prevents the occurrence of recurrences.</abstract>

Department of Morphofunctional Sciences – Pathology

Paranasal sinus mucoceles, therapeutic solution through external surgical approach

AHEAD OF PRINT

Volume 14 (2024): Issue 54 (April 2024)

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Volume 9 (2019): Issue 36 (December 2019)

Volume 9 (2019): Issue 35 (September 2019)

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Volume 8 (2018): Issue 32 (October 2018)

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Volume 7 (2017): Issue 28 (December 2017)

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Volume 5 (2015): Issue 17 (March 2015)

Romanian Journal of Rhinology

Rhinology, as an important part of Otorhinolaryngology, addresses a very frequent and diverse pathology, with important interdisciplinary implications. In the last decades, this medical field was the beneficiary of new technical means for accurate and effective investigation, treatment and research. The needs of modern medicine - over-specialization, interdisciplinary approach and evidence-based medicine, lead to the situation that the international rhinologic societies are the most dynamic and appreciated.  The Romanian Journal of Rhinology is the official scientific publication of the Romanian Rhinologic Society, and it is trying to fill the existing gap in the Romanian ENT literature, promoting modern publishing and criteria according to the international standards. Romanian Journal of Rhinology appears quarterly with the purpose to publish original articles, original clinical reports, clinically relevant experimental studies and short communications presenting new results of general interest. Its aim is to concentrate and provide information concerning care, cure and prevention of different rhinologic disorders and borderline pathology. With a peer review by an important national and international editorial board, the journal provides clinical and clinically related information written by authors from all over the world.  Journal’s business model  Romanian Journal of Rhinology is an Open Access journal. The submission and publication of the articles are free of charge, in both print and electronic publication. The publisher covers all costs – editing, printing, copyediting, typesetting, long-term archiving, journal management.  Romanian Journal of Rhinology is the journal of the Romanian Rhinologic Society; thus, one of the financial sources for publication is represented by the Society from the manuscript fees.  Advertisements represent another important founding source. The decision regarding the type of advertisements, acceptance/rejections, the price offering is made by the Publishing/technical Editor, the Editorial Board having no decision power on this aspect. Advertorials and publicity about pharmacological devices, drugs, supplements related to rhinologic and otolaryngologic pathologies can be taken into consideration. In case of Advertorials, with an important scientific content, the medical data presented will have the approval of the Journal’s Editors.  There is also available the annual subscription for individuals and companies. The contact person is also the Publishing/technical Editor.  Publication schedule  The Romanian Journal of Rhinology is published quarterly:   January-March (publication month: February)  April-June (publication month: April)  July-September (publication month: July)  October-December (publication month: October)  Editorial process  The Romanian Journal of Rhinology uses a standard scheme for the evaluation process of the submitted articles. All manuscripts are strictly reviewed for originality, correctness, methodology, quality of the medical information, suitability for the journal’s medical field, ethical nature.  The Editors reserve the right to refuse any manuscript which does not correspond to the submission guidelines.  Peer-review is the system used to assess the quality of a manuscript before it is published. Independent researchers in the otorhinolaryngology area assess the submitted manuscripts for originality, validity, and significance to help editors determine whether the manuscript should be published in their journal.  After submission:   All manuscript are treated as confidential documents, all being assigned with a registration number (for example, RJR010121 (day of submission)(month of submission) (the last two numbers of the year of submission)). All communications between the editors, the author(s), the reviewers are made by using this identification number.  Technical review performed by the editor-in-chief, associated editors, members of the editorial board analyses – the importance of the subject, presentation clarity, relevance, plagiarism index. Submissions that fail to fulfil all requirements are rejected. This process last for a few days after submission.  Review process. The Romanian Journal of Rhinology has a double-blind reviewing process, in which the reviewers do not know the names of the authors, and the authors do not know who reviewed their manuscript. Therefore, the authors are required to submit a blind manuscript without the authors’ names and affiliations on the title page or in the text and a separate title page with the names of the authors, affiliations, and information about the corresponding author. After the initial assessment for, submissions are sent to at least two experts in the field who are asked to evaluate whether the manuscript is scientifically coherent, easy to read, useful in the field, and whether the manuscript should be accepted, rejected or revised. The review process will take approximately 2 weeks. After the review process is completed, the corresponding author will receive an e- mail about the evaluation results of the submitted manuscript: accepted, revision or rejection. If the e-mail contains suggestions and comments for revising the manuscript, the authors should make the changes and return to the editor within 2 weeks; if not, the manuscript is considered rejected. If the manuscript is accepted for publication by the reviewers, it is forwarded to the Editor-in-Chief. The final decisions are made by the Editor-in-Chief based on the recommendations of reviewers reports and the journal’s editors. Where necessary, they will consult with members of the Editorial Board. The Editor-in-Chief may advice the corresponding author to make necessary revisions in order to publish the article. The final form of the article will be sent to the main author for the last approval from his/her part (if there are minor changes these should be send in no more than 1 week).  The publication process after the article’s submission may take 45 days, average. All accepted articles are assigned with a DOI number.  The Romanian Journal of Rhinology follows the International Committee of Medical Journal Editors (ICMJE) Recommendations for the Conduct, Reporting, Editing and Publication of Scholarly Work in Medical Journals and required ICMJSE to be listed as a journal that follows these recommendations.  Archiving  Sciendo archives the contents of this journal in Portico - digital long-term preservation service of scholarly books, journals and collections.  Plagiarism Policy  The editorial board is participating in a growing community of Similarity Check System's users in order to ensure that the content published is original and trustworthy. Similarity Check is a medium that allows for comprehensive manuscripts screening, aimed to eliminate plagiarism and provide a high standard and quality peer-review process. 