The diagnosis of occupational asthma confirmed by serial peak expiratory flow rate monitoring

Agripina Rașcu 1 , Eugenia Naghi 1 , Claudia Mariana Handra 1 , Ioan Anton Arghir 2 , Dana Mateș 3 , Laura-Georgiana Moise 1 ,  and Marina Ruxandra Oțelea 1
  • 1 Occupational Medicine Department, University of Medicine and Pharmacie “Carol Davila” Bucharest, Romania
  • 2 Faculty of Medicine, University “Ovidius” of Constanța, Romania
  • 3 Occupational Medicine Department, National Institute of Public Health, , Bucharest, Romania


Occupational asthma, the most common occupational respiratory disease in industrialized societies, accounts for 5-10% of all cases of asthma diagnosed in the world. The number of cases is increasing given the development of the “consumer society”. We aim to discuss a case of occupational asthma that we have confirmed using internationally validated methods.

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  • 1. Burge CBSG, Moore VC, Pantin CFA, et al Diagnosis of occupational asthma from time point differences in serial PEF measurements Thorax 2009;64:1032-1036.

  • 2. Moore V, Jaakkola M, Burge S.A systematic review of serial peak expiratory flow measurements in the diagnosis of occupational asthma. Eur Respir J. 2011. 38 (Suppl 55). 4941. Available from:

  • 3. Nicholson PJ, Cullinan P, Taylor AJ, et al. Evidence based guidelines for the prevention, identification, and management of occupational asthma. Occup Environ Med 2005;62:290-9.

  • 4. Suojalehto H, Cullinan P, Aasen TB, et al. Specific inhalation challenges with occupational agents: ERS practical recommendations and clinical guidance. EurRespir J. 2014;43:1573-87.

  • 5. Kopferschmitt-Kubler MC, Pauli G,Tests de provocation bronchique specifiques In L’asthme professionnel Bessot JC, Pauli G(eds), 1999:91-109.

  • 6. GINA. Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention. 2020;1-160. Available from:

  • 7. Gannon P F, Burge P S. Serial peak expiratory flow measurement in the diagnosis of occupational asthma. In: EurRespir J Suppl. 1997; Available from:

  • 8. Cartier A, Kopferschmitt-Kubler MC. Interet de la mesure du debit expiratoire de pointe In In L’asthme professionnel Bessot JC, Pauli G(eds), 1999: 71-81.

  • 9. Newinger G. L’asthme du boulanger In In L’asthme professionnel Bessot JC, Pauli G(eds), 1999:195-205.

  • 10. Rașcu A Astmul bronsic profesional. Ed. Universitara. 2003.

  • 11. Rașcu A, Smărăndescu R. Astmul bronșic profesional In Boli profesionale ale aparatului respirator, Handra CM(ed), Ed. Carol Davila, București; 2019: 22-39.


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