Retrieved cerebral thrombi studied by T 2 and ADC mapping: preliminary results
Article Category: Research Article
Published Online: Nov 20, 2019
Page range: 427 - 433
Received: Oct 03, 2019
Accepted: Oct 22, 2019
DOI: https://doi.org/10.2478/raon-2019-0056
© 2019 Jernej Vidmar, Franci Bajd, Zoran V. Milosevic, Igor J. Kocijancic, Miran Jeromel, Igor Sersa, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Background
Recent advances in MRI technology makes it increasingly more competitive to CT also in the field of interventions. Multi-parametric MRI offers a significant amount of data relevant for characterization of human cerebral thrombi.
Patients and methods
Cerebral thrombi of 17 patients diagnosed with acute stroke were acquired by mechanical thrombectomy. The thrombi were subsequently scanned using a high spatial-resolution 3D
Results
Both MRI mapping techniques enabled a good discrimination among thrombi regions of different water mobility and compaction. Within-sample coefficient of variation of ADC was found most sensitive for discrimination between the thrombi where thrombectomy procedure was performed in a single pass and those where is was performed in two or more passes (p = 0.03). Interestingly, negative correlation was found between the recanalization time and thrombus length (ρ = -0.22).
Conclusions
Preliminary results of presented study shows that pretreatment MRI assessment of thrombi in stroke patients could potentially ease stroke treatment planning. In this study it is shown that within-sample coefficient of variation of ADC could serve for prediction of possible complications during thrombectomy procedures.