Impact of Intense Pulsed Light Therapy on the Quality of Life of Rosacea Patients

Inese Kolontaja-Zaube 1 , 2 , Ināra Ančupāne 1 , Andra Dērveniece 3 , 4 , Aija Žileviča 1  and Ilze Ķikuste 1
  • 1 Faculty of Medicine, University of Latvia, Rīga, Latvia
  • 2 Outpatient clinic “Health and Aesthetics”, , Rīga, Latvia
  • 3 Rīga 1 Hospital, Clinical Centre of Skin and Sexually Transmitted Diseases, , Rīga, Latvia
  • 4 Department of Infectology and Dermatology, Rīga Stradiņš University, LV-1006, Rīga, Latvia


Rosacea is a chronic inflammatory skin disorder affecting predominantly adult patients. The aim of the current investigation was to evaluate clinical response by using quality of life assessment before and after an IPL (intensive pulsed light) therapy course for patients sufferring from rosacea treated in the outpatient clinic “Health and Aesthetics” in Rīga during a one-year period (in 2016). All patients presented with typical clinical symptoms of rosacea on the face — acneiform papules, pustules, telangiectasia, centrofacial erythema, and complaints about flushing and burning. In the current study, 100 rosacea patients treated with IPL therapy were selected. Each patient filled in the quality of life questionnaire before and after two courses of IPL therapy. The interval between IPL therapy sessions was one month. The results reflected comprehensive benefit from IPL therapy for all rosacea patients. No serious side effects from IPL therapy were detected. Side effects like mild eythema after procedure (75%), mild oedema (10%), vesiculation (3%), and hyperpigmentation (8%) were completely resolved within four weeks after completion of treatment. In all patients, quality of life assessment showed a statistically significant increase after two courses of IPL therapy.

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  • Anderson, R. R. (1994). Laser tissue interactions. In: Goldman, M. P., Fitzpatrick, R. E. (eds.). Cutaneous Laser Surgery. Mosby, St. Louis, pp. 9–10.

  • Angermeier, M. C. (1999). Treatment of facial vascular lesions with intense pulsed light. J. Cutan. Laser Ther., 1, 95–100.

  • Belenky, I., Tagger, C., Bingham, A. (2015). Intense pulsed light pulse configuration manipulation can resolve the classic conflict between safety and efficacy. J. Drugs Dermatol., 4 (11),1255–1260.

  • Bitter, P. H. (2000). Noninvasive rejuvenation of photodamaged skin using serial, full-face intense pulsed light treatments. Dermatol. Surg., 26, 835–842.

  • Clementoni, M. T., Gilardino, P., Muti, G. F., Signorini, M., Pistorale, A., Morselli, P. G., Cavina, C. (2006). Intense pulsed light treatment of 1,000 consecutive patients with facial vascular marks. Aesthetic Plast. Surg., 30 (2), 226–232.

  • Goldman, M. P., Weiss, R. A., Weiss, M. A. (2005). Intense pulsed light as a nonablative approach to photoaging. Dermatol. Surg., 31 (9 Pt 2), 1179–1187.

  • Hernández-Pérez, E., Ibiett, E. V. (2002). Gross and microscopic findings in patients submitted to nonablative full-face resurfacing using intense pulsed light: A preliminary study. Dermatol Surg., 28 (8), 651–655.

  • Kawada, A., Shiraishi, H., Asai, M., Kameyama, H., Sangen, Y., Aragane, Y., Tezuka, T. (2002). Clinical improvement of solar lentigines and ephelides with an intense pulsed light source. Dermatol Surg., 28 (6), 504–508.

  • Kimel, S., Svaasand, L. O, Hammer-Wilson, M., Schell, M. J, Milner, T. E, Nelson, J. S., Berns, M. W. (1994). Differential vascular response to laser photothermolysis. J. Invest. Dermatol., 103, 693–700.

  • Liu, J., Liu, J., Ren, Y., Li, B., Lu, S. (2014). Comparative efficacy of intense pulsed light for different erythema associated with rosacea. J. Cosmet. Laser Ther., 16 (6), 324–327.

  • Matts, P. J., Fink, B., Grammer, K., Burquest, M. (2007). Color homogeneity and visual perception of age, health, and attractiveness of female facial skin. J. Amer. Acad. Dermatol., 57 (6), 977–984.

  • Moreno Arias, G. A., Ferrando, J. (2001). Intense pulsed light for melanocytic lesions. Dermatol Surg., 27, 397–400.

  • Neuhaus, I. M., Zane, L. T., Tope, W. D. (2009). Comparative efficacy of nonpurpuragenic pulsed dye laser and intense pulsed light for erythematotelangiectatic rosacea. Dermatol. Surg., 35 (6), 920–928.

  • Raulin, C., Weiss, R. A., Schönermark, M. P (1997). Treatment of essential telangiectasias with an intense pulsed light source (PhotoDerm VL). Dermatol Surg., 23 (10), 941–945.

  • Raulin, C., Greve, B., Grema, H. (2003). IPL technology: A review. Lasers Surg. Med., 32 (2), 78–87.

  • Ross, E. V., Smirnov, M., Pankratov, M., Altshuler, G. (2005). Intense pulsed light and laser treatment of facial telangiectasias and dyspigmentation: Some theoretical and practical comparisons. Dermatol. Surg., 31 (9 Pt 2), 1188–1198.

  • Schroeter, C. A., Neumann, H. A. (1998). An intense light source: The Photoderm VL flashlamp as a new treatment possibility for vascular skin lesions. Dermatol. Surg., 24, 743–748.

  • Schroeter, C. A., Haaf-von Below, S., Neumann, H. A. (2005). Effective treatment of rosacea using intense pulsed light systems. Dermatol. Surg., 31 (10), 1285–1289.

  • Sorg, O., Janer, V., Antille, C., Carraux, P., Leemans, E., Masgrau, E., Saurat, J. H., Salomon, D. (2007). Effect of intense pulsed-light exposure on lipid peroxides and thymine dimers in human skin in vivo. Arch. Dermatol., 143 (3), 363–366.

  • Weiss, R. A., Sadick, N. S. (2000). Epidermal cooling crystal collar device for improved results and reduced side effects on leg telangiectasias using intense pulsed light. Dermatol. Surg., 26 (11), 1015–1018.

  • Weiss, R. A., Weiss, M. A., Beasley, K. L. (2002). Rejuvenation of photoaged skin: 5 years results with intense pulsed light of the face, neck, and chest. Dermatol. Surg., 28 (12), 1115–1119.

  • Wong, W.-R., Shyu, W.-L., Tsai, J.-W., Hsu, K.-H., Pang, J.-H.S. (2009). Intense pulsed light effects on the expression of extracellular matrix proteins and transforming growth factor beta-1 in skin dermal fibroblasts cultured within contracted collagen lattices. Dermatol Surg., 35 (5), 816–825.

  • Yamashita, T., Negishi, K., Hariya, T., Kunizawa, N., Ikuta, K., Yanai, M., Wakamatsu, S. (2006). Intense pulsed light therapy for superficial pigmented lesions evaluated by reflectance-mode confocal microscopy and optical coherence tomography. J. Invest. Dermatol., 126 (10), 2281–2286.


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