Brief Cognitive Monitoring in Multiple Sclerosis Patients in Latvia / Kognitīvo Funkciju Monitorings Multiplās Sklerozes Pacientiem Latvijā

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Cognitive changes are common in people with multiple sclerosis (MS). The neuropsychological testing requires specialised trained staff, time-consuming expert analysis and complicated test result interpretation. An expert committee recommended the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS), which is optimised for small centres. We conducted the Symbol Digit Modalities Test (SDMT) and Brief Visuospatial Memory Test (BVMT), for which the results were comparable with similar results in literature. Most MS patients showed decreased attention and processing speed, while visual memory was generally normal. Cognitive impairment occurrence is not strongly related to Expanded Disability Status Scale (EDSS) score.

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  • Benedict R. H. B. (1997). Brief Visuospatial Memory Test - Revised: Professional Manual. Psychological Assessment Resources Odessa FL. 125 pp.

  • Benedict R. H. Cookfair D. Gavett R. Gunther M. Munschauer F. Garg N. Weinstock-Guttman B. (2006). Validity of the minimal assessment of cognitive function in multiple sclerosis (MACFIMS). J. Int. Neuropsychol. Soc. 12 (4) 549-558.

  • Benedict R. H. Fischer J. S. Archibald C. J. Arnett P. A. Beatty W. W. Bobholz J. Chelune G. J. Fisk J. D. Langdon D. W. Caruso L. Foley F. LaRocca N. G. Vowels L. Weinstein A. DeLuca J. Rao S. M. Munschauer F. (2002). Minimal neuropsychological assessment of MS patients: A consensus approach. Clin. Neuropsychol. 16 (3) 381-397.

  • Deloire M. Ruet A. Hamel D. Bonnet M. Brochet B. (2010). Early cognitive impairment in multiple sclerosis predicts disability outcome several years later. Multiple Sclerosis 16 (5) 581-587.

  • Feinstein A. DeLuca J. Baune B. T. Filippi M. Lassman H. (2013). Cognitive and neuropsychiatric disease manifestations in MS. MS Related Disord. 2 (1) 2-14.

  • Guimaraes J. Sá J. (2012). Cognitive dysfunction in multiple sclerosis. Front Neurol. 3 (74) 1-8.

  • Langdon D. W. Amato M. P. Boringa J. Brochet B. Foley F. Fredrikson S. Hämäläinen P. Hartung H. P. Krupp L. Penner I. K. Reder A. T. Benedict R. H. B. (2012). Recommendations for a Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS). Multiple Scler. J. 18 (6) 891-898.

  • Lynch S. G. Parmenter B. A. Denney D. R. (2005). The association between cognitive impairment and physical disability in multiple sclerosis. Mult. Scler. 11 (4) 469-476.

  • Parmenter B. A. Testa M. S. Schretlen D. J. Weinstock-Guttman B. Benedict R. H. B. (2010). The utility of regression-based norms in interpreting the minimal assessment of cognitive function in multiple sclerosis (MACFIMS). J. Int. Neuropsychol. Soc. 16 (1) 6-16.

  • Penner I. K. Kandziora P. Poettgen J. Heesen C. Lang M. Schreiber H. (2015). German Validation of the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS). Neurology 84 (14) P5.196

  • Rao S. M.; Cognitive Function Study Group of the National Multiple Sclerosis Society. (1990). A Manual for the Brief Repeatable Battery of Neuropsychological Tests in Multiple Sclerosis. Medical College of Wisconsin Milwaukee.

  • Rao S. M. Leo G. J. Bernardin L. Unverzagt F. (1991). Cognitive dysfunction in multiple sclerosis. I. Frequency patterns and prediction. Neurology 41 (5) 685-691.

  • Smith A. (2011). Symbol Digit Modalities Test (SDMT) Manual USA: Western Psychological Services. Doctoral dissertation USA. 22 pp.

  • Strober L. Englert J. Munschauer F. Weinstock-Guttman B. Rao S. Benedict R. H. (2009). Sensitivity of conventional memory tests in multiple sclerosis: Comparing the Rao Brief Repeatable Neuropsychological Battery and the Minimal Assessment of Cognitive Function in MS. Multiple Sclerosis 15 (9) 1077-1084.

  • Vanotti S. Benedict R. Caceres F. (2015). Validation of the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) in Argentina. Neurology 84 (14) P5.201

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