Late Onset of Pancreatic Metastases from Renal Cell Carcinoma. A Case Report

Vesna Janevska 1 , Aleksandar Shumkovski 2 , Dafina Nikolova 3 , Learta Asani 4 , Stefan Pandilov 1 , and Vlatko Karanfilovski 1
  • 1 Institute for Pathology, Faculty of Medicine, Macedonia, Skopje
  • 2 University Clinic for Abdominal Surgery, , Republic of North Macedonia, Skopje
  • 3 University Clinic of Gastroenterohepatology, , Republic of North Macedonia, Skopje
  • 4 City General Hospital 8th September, , Republic of North Macedonia, Skopje


Metastasis of renal cell carcinoma (RCC) to the pancreas is a rare entity accounting only 0.25–3% of all pancreatic tumors. We present a rare case of isolated three focal pancreatic metastases from RCC, occurring 15 years after the left nephrectomy. The majority of the pancreatic metastases are asymptomatic, as it was in case of our patient excluding the weight loss for the last three months. We demonstrate the importance of the medical history, radiological examinations, histological and immunohistochemical analysis in making a definitive diagnosis.

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