Acute Thyroiditis Associated with Brucellosis: A Case Report

Open access

Abstract

Brucella thyroiditis represents an extremely rare focal form of brucellosis. In this case report we describe a 55 years old male, diagnosed with brucellosis and peripheral arthritis with subsequent development of acute thyroiditis. The symptoms duration consistent with brucellosis started two weeks before establishing the diagnosis. Only a day after diagnosis and initiation of antibrucellar treatment, acute non-suppurative thyroiditis suddenly manifested. Thyroiditis was diagnosed with clinical inspection and confirmed by ultrasound investigation. With the appropriate antibrucellar treatment, complete cure of thyroid affection was reached in ten days and the patient remained well during the follow-up period of two and a half years. In conclusion, in brucellosis endemic regions brucellosis should be included in the diagnostic consideration in patients with acute non-suppurative thyroiditis. Early recognition and adequate treatment of brucella thyroiditis results in favorable outcome.

If the inline PDF is not rendering correctly, you can download the PDF file here.

  • 1. Bosilkovski M. Brucellosis: It is not only Malta! In: Sing A Ed. Zoonoses-infections affecting humans and animals. Focus on public health aspects. Dordrecht Heidelberg New York London: Springer; 2014: p. 287–315.

  • 2. Bosilkovski M Stojanov A Stevanovic M et al. Impact of measures to control brucellosis on disease characteristics in humans: experience from an endemic region in the Balkans. Infect Dis (Lond). 2018; 50: 340–345. doi: 10.1080/23744235.2017.1407037.

  • 3. Kucukbayrak A Yildirim M Ozdemir D et al. Subacute thyroiditis due to brucellosis case report and review of the literature. SETB. 2007; 41(2): 51–54.

  • 4. Starakis I Mazokopakis EE Bassaris H. Unusual manifestations of brucellosis: a retrospective case series in a tertiary care Greek university hospital. East Mediterr Health J. 2010; 16(4): 365–370.

  • 5. Akdemir Z Karaman E Akdeniz H et al. Giant thyroid abscess related to postpartum Brucella infection. Case Rep Infect Dis. 2015; 646209. doi: 10.1155/2015/646209

  • 6. Harman R Asik Z Inan D et al. Thyroid Abscess Due To Brucellosis: Case report. Trakya Univ Med Fak Jour 2010; 27: 438–439.

  • 7. Karsen H Akdeniz H Erten R et al. Thyroid gland abscess due to Brucella melitensis. Dicle Medical Journal 2011; 38(2): 225–227.

  • 8. Sunnetcioglu M Ceylanb MR Atmacac M et al. Rare brucellosis involvement: Thyroid gland abscess. Eastern J Med. 2015; 20: 62–64.

  • 9. Alinaghian M Avijgan M. Brucellosis Presented as Thyroiditis: A Rare Case Report. Adv Infect Dis 2016; 6: 157–162.

  • 10. Vermiglio F Stassi G Finocchiaro MD et al. Thyroiditis due to Brucella melitensis. J Endocrinol Invest 1995; 18(4): 308–310.

  • 11. Fatani A Alesa A Alfaidi A et al. Brucella Induced Thyroiditis: Case Report and Literature Review. Egypt J Hosp Med 2018 Vol. 70 (10) Page 1742–1744.

  • 12. Sirmatel F Akarsu E. Case report. A brucellosis case with subacute thyroiditis. Mikrobiyol Bult 2002; 38(2): 149–153.

  • 13. Uzunlar AK. Resembling Carcinoma Thyroiditis due to Brucella melitensis Case. Firat Med J 2008; 13: 205–206.

  • 14. Mousa AR al-Mudallal DS Marafie A. Brucella thyroiditis. J Infect 1989; 19(2): 287–288.

  • 15. Buzgan T Karahocagil MK Irmak H et al. Clinical manifestations and complications in 1028 cases of brucellosis: a retrospective evaluation and review of the literature. Int J Infect Dis. 2010; 14: 469–478. doi: 10.1016/j.ijid.2009.06.031.

  • 16. Bosilkovski M Krteva L Dimzova M et al. Human brucellosis in Macedonia – 10 years of clinical experience in endemic region. Croat Med J 2010; 51: 327–336.

  • 17. Roushan H Mohrez M Smailnejad Gangi SM et al. Epidemiological features and clinical manifestations in 469 adult patients with brucellosis in Babol Northern Iran. Epidemiol Infect. 2004; 132(6): 1109–1114.

  • 18. Colmenero JD Reguera JM Martos F et al. Complications associated with Brucella melitensis infection: a study of 530 cases. Medicine. 1996; 75: 195–211.

Search
Journal information
Impact Factor


CiteScore 2017: 0.45

SCImago Journal Rank (SJR) 2018: 0.177

Metrics
All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 172 172 51
PDF Downloads 89 89 31