Published Online: Feb 13, 2020
Page range: 53 - 60
Received: May 22, 2019
Accepted: Jul 01, 2019
DOI: https://doi.org/10.2478/orvtudert-2019-0007
Keywords
© 2019 Kelemen Hajnal et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Triptans are specific drugs for migraine attack, their use leads to selective vasoconstriction, while the inflammatory condition that usually occurs during migraine is reduced. The structurally indolamine derivatives are selective agonists of the serotonin 1B/1D receptor. This review presents the history, representatives, production, and physico-chemical properties of triptans, but also discusses their pharmacological properties and mechanism of action.