Possible Deleterious Impact of Glyphosate and its Commercial Formulation in Reproductive Health of Fishes

I. Argou-Cardozo 1  and F. Zeidán-Chuliá 2 , 3
  • 1 Specialization Course in Public Management and Regional Development, Faculty of Administration and Tourism, 96010-610, Pelotas, Brazil
  • 2 Departamento de Ciencias Biomédicas Básicas, Facultad de Ciencias Biomédicas y de la Salud, 28670, Villaviciosa de Odón, Spain
  • 3 Faculty of Medicine, 20520, Turku, Finland


Glyphosate (GLY) is the active ingredient of Roundup® and it is the most utilized herbicide worldwide in the maintenance of conventional agricultural crops, and lawns in parks. A growing number of studies have associated environmental GLY to different pathologies such as obesity, diabetes, heart disease, Alzheimer’s disease, depression, and autism. Different fish species have been used for a long time as experimental biological models to measure the environmental impact of different substances. Therefore, the present study approached the possible association between the exposure to GLY / Roundup® and the ecotoxicological impact on fish reproductive health. With this goal, we performed a comprehensive analysis of the literature and its content by systematic review of international databases. Two independent electronic searches were performed on Medline / PubMed and Scielo for identifying relevant studies published in English up to September 2019. The application of inclusion / exclusion criteria settled the boundaries for this systematic review and after qualitative analysis of the data; we found evidences that suggest a link between the exposure to GLY / Roundup® with deleterious effects on reproductive health in eight different species of fish.

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