Asymptomatic Unilateral Ovarian Leiomyoma in a German Shepherd Bitch

Alessandro Pecile 1 , Debora Groppetti 1 , Valeria Grieco 1 , Gabriele Barella 1 , Melania Moioli 1 , and Stefano Faverzani 1
  • 1 Department of Veterinary Medicine, Faculty of Veterinary Medicine, Università degli Studi di Milano, Milano, Italy

Abstract

This report shows for the first time clinical imaging (ultrasound and computed tomography), histological and immunohistochemical findings of an ovarian leiomyoma, coincidentally diagnosed in an asymptomatic unmated nulliparous ten year-old German shepherd bitch concurrently suffering from multiple mammary tumors. A thorough examination allowed the differentiation of ovarian leiomyoma from other spindle cell tumors. An accurate description of the diagnostic procedures useful in the managing of ovarian leiomyoma could provide valuable information to veterinary practitioners. Indeed, despite its rarity and nonspecific symptoms, ovarian leiomyoma may also affect the dog with an unknown potential risk.

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  • 1. Lalwani, N., Shanbhogue, A.K., Bhargava, P., Vikram, R., Prasad, S.R. (2012). Rare, miscellaneous primary ovarian neoplasms: spectrum of crosssectional imaging. Current Problems in Diagnostic Radiology 41, 73-80. http://dx.doi.org/10.1067/j.cpradiol.2011.07.026 PMid:22285004

  • 2. Murakami, M., Uehara, H., Nishimura, M., Iwasa, T., Ikawa, H. (2010). A huge ovarian smooth muscle tumor: a case report. The Journal of Medical Investigation 57, 158-162. http://dx.doi.org/10.2152/jmi.57.158 PMid: 20299756

  • 3. MacLachlan, N.J., Kennedy, P.C. (2002). Tumors of the genital systems. In: Meuten D.J. (Ed.), Tumors in domestic ani¬mals IV (pp 547-574). Iowa USA: Iowa State University Press. http://dx.doi.org/10.1002/9780470376928.ch11

  • 4. Sforna, M., Brachelente, C., Lepri, E., Mechelli, L. (2003). Canine ovarian tumors: a retrospective study of 49 cases. Vet Res Commun. 27 Suppl. 1, 359-366. http://dx.doi.org/10.1023/B:VERC.0000014180.77684.52

  • 5. Sathya, S., Linn, K. (2014). Regression of a vaginal leiomyoma after ovariohysterectomy in a dog: a case report. J Am Anim Hosp Assoc. 50, 424-428. http://dx.doi.org/10.5326/JAAHA-MS-6082 PMid:25251430

  • 6. Gunasekaran, I., Phansalkar, M., Palo, L.B., Varghese, R.G. (2015). Ovarian leiomyoma along with uterine leiomyomata: a common tumor at an uncommon site. Journal of Clinical and Diagnostic Research 9, ED01-ED02. http://dx.doi.org/10.7860/JCDR/2015/13378.6703 PMid:26674537 PMCid:PMC4668420

  • 7. Howe, L.M. (2006). Surgical methods of contraception and sterilization. Theriogenology 66, 500-509. http://dx.doi.org/10.1016/j.theriogenology.2006.04.005 PMid:16716381

  • 8. Rutteman, G.R., Withrow, S.J., Macewen, E.G. (2001). Tumors of the mammary gland. In J. Withrow, E.G. MacEwen (Eds.), Small Animal Clinical Oncology (pp. 538-556). St. Louis USA: Elsevier Sanders.

  • 9. Grieco, V., Locatelli, C., Riccardi, E., Brambilla, P. (2008). A case of two different tumors in the heart of a dog. J Vet Diagn Invest. 20, 365-368. http://dx.doi.org/10.1177/104063870802000320 PMid:18460629

  • 10. Hsu, S.M., Raine, L., Fanger, H. (1981). Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem. 29, 577-580. http://dx.doi.org/10.1177/29.4.6166661 PMid:6166661

  • 11. Wei, C., Lilic, N., Shorter, N., Garrow, E. (2008). Primary ovarian leiomyoma: a rare cause of ovarian tumor in adolescence. J Pediatr Adolesc Gynecol. 21, 33-6. http://dx.doi.org/10.1016/j.jpag.2007.07.001 PMid:18312799

  • 12. Lewill, M.F., Sung, R., Oliva, E., Prat, J., Young, R.H. (2004). Smooth muscle tumors of the ovary: a clinicopathologic study of 54 cases emphasizing prognostic criteria, histologic variants, and differential diagnosis. Am J Surg Pathol. 28, 1436-1451. http://dx.doi.org/10.1097/01.pas.0000141393.99300.d0 PMid: 15489647

  • 13. Shiwa, N., Boonsriroj, H., Kimitsuki, K., Shimatsu, T., Park, C.H. (2016). The co-existence of a myxoid liposarcoma and leiomyoma in the same ovarian mass of a dog. J Vet Med Sci 78(3): 467-471. http://dx.doi.org/10.1292/jvms.15-0467 PMid:26522811 PMCid:PMC4829519

  • 14. Mathew, M., Gonsalves, H., Al-Azawi, S., Saparamadu, P.A. (2013). Asymptomatic ovarian mucinous cystadenoma with a solid mural leiomyoma: Case report and brief review. Sultan Qaboos Univ Med J. 13, 127-131. http://dx.doi.org/10.12816/0003206 PMid:23573393 PMCid:PMC3616778

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