1 Division of Veterinary Surgery and Radiology, Faculty of Veterinary Science & AH, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, India
2 Veterinary Clinical Service Complex, Faculty of Veterinary Science & AH, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, India
3 Veterinary Clinical Service Complex, Faculty of Veterinary Sciences & AH, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Srinagar, 190006, Jammu and Kashmir, India. Phone: +91-9419095830
4 Centre of Animal Biotechnology, Faculty of Veterinary Science & AH, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, India
5 Department of Animal Production, College of Food and Agricultural Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia
Goats (n=12) undergoing laparoscopy assisted embryo transfer were randomly allotted to two groups (I and II) and injected lignocaine hydrochloride (4mg/kg) or ropivacaine hydrochloride (1mg/kg) at the lumbosacral epidural space. The animals were held with raised hind quarters for the first three minutes following injection. Immediately after induction of regional anaesthesia, they were restrained in dorsal recumbency in the Trendelenburg position in a cradle. Laparoscopy was performed after creating pneumoperitoneum using filtered room air. The mean (± S.E) induction time in animals of group I was significantly shorter (5.33 ± 0.61 min) than those belonging to group II (12.66 ±1.99 min). Complete analgesia developed throughout the hind quarters and abdomen for 30 min and 60 min in group I and II animal’s respectively. Unlike animals of group I, group II goats continued to show moderate analgesia for 180 minutes. The motor activity returned after a lapse of 130.00 ± 12.64 min and 405.00 ± 46.31 min respectively. Occasional vocalization and struggling was noticed in two goats one from each group irrespective of the surgical manipulations during laparoscopy. The rectal temperature and respiration rates showed only non-significant increase, but the heart rate values were significantly higher (P < 0.5) up to 150 min in animals of both the groups when compared to their baseline values. From this study, it was concluded that both anaesthetic agents produced satisfactory regional anaesthesia in goats undergoing laparoscopy. However, considering the very long delay in regaining the hind limb motor activity, the use of ropivacaine may not be recommended for this purpose. Supplementation of sedative/tranquilizer with lumbosacral epidural anaesthesia needs evaluation.
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1. Shin S.T. Jang S.K. Yang H.S. Lee OK. Shim Y.H. Choi W.II. Lee D.S. Lee G.S. Cho J.K. Lee Y.W. (2008). Laparoscopy vs. laparotomy for embryo transfer to produce transgenic goats (Capra hircus). J. Vet. Sci. 9 103-107. http://dx.doi.org/10.4142/jvs.2008.9.1.103
2. Dovenski T. Trojacanec P. Petkov V. Popovska- Percinic F. Kocoski Lj. Grizelj J. (2012).
Laparoscopy-promising tool for improvement of reproductive efficiency of small ruminants. Mac Vet Rev 2012; 35(1): 5 - 11.
3. Hall L.W. Clarke K.W. Trim C.M. (2001).
Veterinary anaesthesia fourth edition W.B Saunders Tottenham court road London (U.K).
4. Lamont L.A. (2002). Local anaesthetics in veterinary anaesthesia and pain management secrets.
First edition. Hanley and Belfus INC. Medical publishers Philadelphia.
5. Skarda R.T. Tranquilli W.J. (2007). Local and regional anesthetic and analgesic techniques: Ruminant and swine. Lumb & Jones’ Veterinary Anesthesia and Analgesia. Fourth edition. Ames IA: Blackwell Publishing.
6. Edmondson M.A. (2014). Local and regional anesthetic techniques in farm animal anesthesia.
Lin H and Walz P (Eds.) fi rst edition Wiley Blackwell Lowa USA.
7. Gray P.R. Mc Donell W.N. (1986). Anesthesia in goats and sheep. Part I. Local analgesia. Compen.
9. Ala-Kokko T.I. Partanen A. Kainen J. Kiviluoma K. Alahuhta S. (2000). Pharmacokinetics of 0.2 % ropivacaine and 0.2 % bupivacaine following caudal blocks in children. Acta Anaesthesiol. Scand. 44 1099-1102. http://dx.doi.org/10.1034/j.1399-6576.2000.440911.x PMid:11028730
10. Singh K. Kinjavdekar. Amarpal. Aithal H.P. Gopinathan A. Singh G.R. Singh T. Pawde A.M. Pratap K. (2005). Clinicophysiological and hematobiochemical effects of epidural ropivacaine in uremic and healthy caprines. Indian J. Vet. Surg. 26 11-15.
11. Ahmad R. Shukla B.P. Jain R. (2011).
Clinicophysiological changes following epidural analgesia by bupivacaine ropivacaine or ropivacaine-xylazine combination in goats. Indian J.
Vet. Surg. 32 57-58.
12. Ahmad R. Shukla B.P. (2013). Haematobiochemical changes following epidural analgesia by bupivacaine ropivacaine and ropivacaine- xylazine combination in goats. Indian J. Field Vet. 8 47-51.
13. Kuthiala G. Choudhary G. (2011). Ropivacaine: A review of its pharmacology and its clinical use. Ind.
J. Anaesth. 55104-110.
14. Amarpal. Kinjavdekar H. Aithal H.P. Singh G.R. Pawde A. Singh T. Sharma N. Pratap K. (2007). Comparison of two doses of ropivacaine for lumbosacral epidural analgesia in buffalo calves (Bubalus bubalis). Vet. Rec. 160 766-769. http://dx.doi.org/10.1136/vr.160.22.766
15. Kinjavdekar P. Aithal H.P. Amarpal. Pawde A.M. Pratap K. Singh G.R. (2006). Potential effect of romifidine with lidocaine administration in goats. Small Rumin. Res. 64 293-304. http://dx.doi.org/10.1016/j.smallrumres.2005.04.029
16. Dadafarid H. Najafpour A. (2008). Hematochemical changes following epidural analgesia by bupivacaine ketamine and their combination in Chall sheep. J. Anim. Vet. Adv. 7 1524-1527.
17. Adetunji A. Ajadi R.A. Opia R.E. (2002). A comparison of epidural anaesthesia with xylazine bupivacaine and bupivacaine/xylazine mixture in West African dwarf goats. Isr. J. Vet Med. 57 74-80.
18. De Rossi R. Junqueira A.L. Lopes R.A. Beretta M.P. (2005). Use of ketamine or lidocaine or in combination for subarachnoid analgesia in goats. Small Rumin. Res. 59 95-101. http://dx.doi.org/10.1016/j.smallrumres.2004.11.009
19. Rostami M. Vesal N. (2012). The effects of adding epinephrine or xylazine to lidocaine solution for lumbosacral epidural analgesia in fat-tailed sheep. J.
S. Afri. Vet. Assoc. 83 1-7. http://dx.doi.org/10.4102/jsava.v83i1.1
20. Amnikov B. (1999). Epidural administration of xylazine-lidocaine mixture in sheep-analgesic and cardiopulmonary effects. Vet. Arhive 69 327-333.
21. Franz S. Dadak A.M. Khol J.L. Damaso A. Baumgartner W. (2009). Laparoscopic performed cystotomy and catheter implantation in male sheep.
Vet. Med. 54 367-373.
22. Araujo M.A. Albuquerque V.B. Deschk M. Santos G.G.F. Rodrigues C.A. Oliva V.N.L.S. Santos P.S.P. (2012). Cardiopulmonary and analgesic effects of caudal epidurally administered ropivacaine in cattle. Vet. Anaesth. Analg. 39 409-413. http://dx.doi.org/10.1111/j.1467-2995.2012.00726.x PMid:22574815
23. Skarda R.T. Muir W.W. (2001). Analgesia hemodynamic and respiratory effects of caudal epidurally administered ropivacaine hydrochloride in mares. Vet. Anaesth. Analg. 28 61-74. http://dx.doi.org/10.1046/j.1467-2995.2001.00025.x
24. Duke T. Caulkett N.A. Ball H.S. Remedios A.M. (2000). Comparative analgesia and cardiopulmonary effects of bupivacaine and ropivacaine in the epidural space of conscious dogs. Vet. Anaesth.
30. De Rossi R. Silva-Neto A.B. Pompermeyer C.T.D. Frazílio F.O. Paulo H.A. Jardim A.C.L. (2012).
The efficacy and safety of levobupivacaine administered by lumbosacral epidural route in conscious sheep. Res. Vet. Sci. 92 278-282. http://dx.doi.org/10.1016/j.rvsc.2010.11.006
31. Conzemius M.G. Hill C.M. Sammarco J.L. Perkowski S.Z. (1997). Correlation between subjective and objective measures used to determine severity of postoperative pain in dogs. J. Am. Vet. Med. Assoc. 210 1619-1622.
32. Lin H. (2014). Commonly used preanesthetics.
In: Farm animal anesthesia. Lin H and Walz P (editors) first edition Wiley Blackwell Lowa USA. http://dx.doi.org/10.1002/9781118886700