Monitoring thoracic fluid content using bioelectrical impedance spectroscopy and Cole modeling

Heart failure is a chronic disease marked by frequent hospitalizations due to pulmonary fluid congestion. Monitoring the thoracic fluid status may favor the detection of fluid congestion in an early stage and enable targeted preventive measures. Bioelectrical impedance spectroscopy (BIS) has been used in combination with the Cole model for monitoring body composition including fluid status. The model parameters reflect intracellular and extracellular fluid volume as well as cell sizes, types and interactions. Transthoracic BIS may be a suitable approach to monitoring variations in thoracic fluid content.