Original Research. The Influence of Desquamative Gingivitis on Periodontal Health

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Background: Desquamative gingivitis (DG) is a non-plaque-induced, blistering and painful condition occurring most frequently on the labial aspect of the attached gingiva of anterior teeth. The incidence of DG is highest around 50 years of age, and usually indicates the presence of oral or systemic diseases. The purpose of our study was to determine the impact of DG on periodontal health by recording the plaque index, gingival index and gingival bleeding index in a group of patients with DG, compared to healthy controls. Materials and methods: Recordings of specific indices were performed in a group of 26 patients with DG and compared with 24 healthy individuals. These were followed by radiographic examinations in order to assess the loss of marginal alveolar bone. Results: The results showed that patients with DG had a statistically significant increase in periodontal indices, with more gingival inflammation and plaque retention compared to the control group (p <0.05). The highest scores for gingival inflammation were recorded in patients with DG, but on radiographic evaluation the difference was related only to gender, men being more affected by alveolar bone loss in both groups (p <0.05). Conclusions: The incidence and severity of gingival inflammation proved to be higher in patients with DG, which calls for better preventive and maintenance treatment protocols in this group of patients. Early diagnosis and initial-phase periodontal treatment are very important in preventing further tissue breakdown.

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  • 1. Lo Russo L Fedele S Guiglia R et al. Diagnostic pathways and clinical significance of desquamative gingivitis. J Periodontol. 2008;79:4-24.

  • 2. Leao J Ingafon M Khan A Scully C Porter S. Desquamative gingivitis: retrospective analysis of disease associations of a large cohort. Oral Diseases. 2008;14:556-560.

  • 3. Lo Russo L Fierro G Guiglia R et al. Epidemiology of desquamative gingivitis: evaluation of 125 patients and review of the literature. Int J Dermatol. 2009;48:1049-1052.

  • 4. Roopashree MR Goudhalekar RV Shashikanth MC George J Thippeswamy SH Skula A. Pathogenesis of oral lichen planus: a review. J Oral Pathol Med. 2010;39:729-734.

  • 5. Said S Golitz L. Vesiculobullous eruptions of the oral cavity. Otolaryngol Clin North Am. 2011;44:133-160.

  • 6. Sirois D Leigh JE Sollecito TP. Oral pemphigus vulgaris preceding cutaneous lesions: recognition and diagnosis. J Am Dent Assoc. 2000;131:1156-1160.

  • 7. Akman A Kacaroglu H Yilmaz E Alpsoy E. Periodontal status in patients with pemphigus vulgaris. Oral Dis. 2008;14:640-643.

  • 8. Lopez-Jornet P Camaco-Alonso F. Periodontal conditions in patients with oral lichen planus: a pilot study. Quintessence Int. 2012;43:147-152.

  • 9. Lo Russo L Gallo C Pellegrino G et al. Periodontal clinical and microbiological data in desquamative gingivitis patients. Clin Oral Investig. 2014;18:917-925.

  • 10. Scully C Carrozzo M. Oral mucosal disease: lichen planus. Br J Oral Maxillofac Surg. 2008;46:15-21.

  • 11. Lopez-Jornet P Camacho-Alonso F. Application of a motivation-behavioral skills protocol in gingival lichen planus: a short-term study. J Periodontol. 2010;81:1449-1454.

  • 12. Thorat MS Raju A Pradeep AR. Pemphigus vulgaris: effects on periodontal health. J Oral Sci. 2010;52:449-454.

  • 13. Lim HD Kang JK Lee YM Shim YJ. The correlation between desquamative gingivitis associated diseases and plaque-induced periodontal disease. J Oral Med Pain. 2015;40:135-139.

  • 14. Salgado DS Jeremias F Capela MV Onofre MA Massucato EM Orrico SR. Plaque control improves the painful symptoms of oral lichen planus gingival lesions. A short-term study. J Oral Pathol Med. 2013;42:728-732.

  • 15. Ertugrul AS Dursun R Dundar N Avunduk MC Hakki SS. MMP-1 MMP-9 and TIMP-1 levels in oral lichen planus patients with gingivitis or periodontitis. Arch Oral Biol. 2013;58:843-852.

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