Gastroesophageal reflux disease (GERD) is a very common digestive disorder, which occurs when the acidic contents of the stomach returns into the esophagus to some extent, reaching the mouth, thereby increasing the frequency of dental erosion and caries. Since saliva plays a huge role in oral homeostasis, it is important to examine the role of this parameter in the appearance of the above mentioned oral lesions. The aim of our study was evaluate the oral condition of children suffering from reflux disease and to assess the relationship between salivary pH and the incidence of dental erosion and caries. In this prospective study we examined 25 children diagnosed with GERD, referred for hospitalization. Bedside intra-oral examination (DMFT index, gingival index) and strip method pH value determination was performed. We observed that patients with low pH values had increased caries frequency, and dental erosion was also noticeable. Statistical significance was determined comparing the DMFT index in groups with different pH values. We concluded that the high number of erosions is closely related to gastroesophageal reflux disease, as a consequence of the low pH value, which represents the main cause of oral manifestations in GERD.
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1. Tulassay Zs. A belgyógyászat alapjai 1. Budapest: Medicina Könyvkiadó Zrt. 2010; p. 245-251.
2. Nyárasdy I Bánóczy J. Preventív fogászat. Budapest: Medicina Könyvkiadó Zrt. 2009; p. 14-32.
3. Ersin NK Onçağ O Tümgör G Aydoğdu S Hilmioğlu S. Oral and dental manifestations of gastroesophageal reflux disease in children: a preliminary study. Pediatr Dent. 2006;28:279-284.
4. Di Fede O Di Liberto C Occhipinti G et al. Oral manifestations in patients with gastroesophageal reflux disease: a single-center case-control study. J Oral Pathol Med. 2008;37:336-340.
5. Ranjitkar S Smales RJ Kaidonis JA. Oral manifestations of gastroesophageal reflux disease. J Gastroenterol Hepatol. 2012;27:21-27.
6. Kislig K Wilder-Smith CH Bornstein MM Lussi A Seemann R. Halitosis and tongue coating in patients with erosive gastroesophageal reflux disease versus nonerosive gastresophageal reflux disease. Clin Oral Investig. 2013;17:159-165.
7. Farahmand F Sabbaghian M Ghodousi S Seddighoraee N Abbasi M. Gastroesophageal reflux disease and tooth erosion: a cross-sectional observational study. Gut Liver. 2013;7:278-281.
8. Ranjitkar S Kaidonis JA Roger J. Smales Gastroesophageal Reflux Disease and Tooth Erosion. International Journal of Dentistry. 2012;2012:479850.
9. Pace F Pallotta S Tonini M Vakil N Bianchi Porro G. Systematic review: gastroesophageal reflux disease and dental lesions. Aliment Pharmacol Ther. 2008;27:1179-1186.
10. Dahshan A Patel H Delaney J Wuerth A Thomas R Tolia V. Gastroesophageal reflux disease and dental erosion in children. J Pediatr. 2002;140:474-478.
11. O’Sullivan EA Curzon ME Roberts GJ Milla PJ Stringer MD. Gastroesophageal reflux in children and its relationship to erosion of primary and permanent teeth. Eur J Oral Sci. 1998;106:765-769.
12. Linnett V Seow WK Connor F et al. Oral health of children with gastroesophageal reflux disease: A controlled study. Aust Dent J. 2002;47:156-162.
13. Fábián G Gábris K Tarján I. Gyermekfogászat Fogszabályozás és Állcsont-Ortopédia I./4. Budapest: Semmelweis Kiadó 2013.
14. Vályi P. Dentálhigiénikusok kézikönyve. Szeged: Szegedi Tudományegyetem 2014/2015; p. 31-36.
15. Featherstone JDB. Dental caries: a dynamic disease process. Austr Dent J. 2008;53:286-291
16. Rosztóczky A Wittmann T. Refluxbetegség - gyomorsav okozta bántalmak. Budapest: Gasztroenterológia Springmed Kiadó KFT 2006; p. 24-27.
17. de Almeida Pdel V Grégio AM Machado MA de Lima AA Azevedo LR. Saliva Composition and Functions: A Comprehensive Review. J Contemp Dent Pract. 2008;9:72-80.
18. Øgaard B Alm AA Larsson E Adolfsson U. A prospective randomized clinical study on effects of amine fluoride/stannous fluoride toothpaste/ mouth rinse on plaque gingivitis and initial caries lesion development in orthodontic patients. Eur J Orthod. 2006;28:8-12.
19. Linnett V Seow WK Connor F Shepherd R. Oral health of children with gastroesophageal reflux disease: A controlled study. Aust Dent J. 2002;47:156-162.