Introduction: Pilomatrixoma or pilomatricoma is a benign appendageal growth, originating from hair cortex cells.
Case presentation: We present an unusual case of a 65-year-old female patient who has been diagnosed and treated for a presumed recurrent furunculosis localized on the abdominal area. Ultrasonography raised the suspicion of pilomatrixoma. A large excision was performed and histopathology confirmed the diagnosis.
Conclusions: Ultrasonography could be a simple and reliable diagnostic tool in daily practice.