Risk Factors for Congenital Hearing Loss: Which Are the Most Relevant?

Open access

Abstract

Introduction: Congenital hearing loss is a multifactorial disease that affects mostly premature newborns exposed to certain risk factors. The recent widespread introduction of newborn hearing screening in Tîrgu Mureş, Romania prompted the need for a multidisciplinary centralized study on the subject.

Case series presentation: We collected data from 340 neonates born in 2014 who had undergone neonatal hearing screening with otoacoustic emissions. Our focus group consisted of 137 neonates with a gestational age of less than 37 weeks. We collected data on the pregnancy, birth, and perinatal period, and then analyzed the impact of infections, treatments — with or without ototoxic potential, hypoxia, mechanical ventilation, intrauterine malnutrition, and the presence of malformations. Premature neonates showed a significantly higher number of REFER results than those with a normal gestational age. The rates of low birthweight, head circumference, and infant length; low Apgar scores; hypoxia in the perinatal period; the presence of placental pathology, mechanical ventilation, and perinatal infections; and the concomitant potentially ototoxic treatment were significantly higher in the REFER group. The age of the mother, bilirubin levels, and oxytocin use during birth did not prove to be relevant.

Conclusions: Known risk factors can cause hearing loss in a considerable number of newborns and mandate a multidisciplinary approach to the problem at hand. The referral of these patients to an ENT specialist and their correct management according to an individualized hearing recovery plan is crucial

If the inline PDF is not rendering correctly, you can download the PDF file here.

  • 1. Wroblewska-Seniuk KE Dabrowski P Szyfter W Mazela J. Universal newborn hearing screening: methods and results obstacles and benefits. Pediatr Res. 2017. doi: 10.1038/pr.2016.250. [Epub ahead of print]

  • 2. Vos B Senterre C Lagasse R SurdiScreen Group Levêque. Newborn hearing screening programme in Belgium: a consensus recommendation on risk factors. BMC Pediatr. 2015;15:160.

  • 3. Kraft CT Malhotra S Boerst A Thorne MC. Risk indicators for congenital and delayed-onset hearing loss. Otol Neurotol. 2014;35:1839-1843.

  • 4. Kim SH Choi BY Park J Jung EY Cho SH Park KH. Maternal and Placental Factors Associated with Congenital Hearing Loss in Very Preterm Neonates. Pediatr Neonatol. 2016; S1875-9572(16)30102-4.

  • 5. Ječmenica J Bajec-Opančina A Ječmenica D. Genetic hearing impairment. Childs Nerv Syst. 2015;31:515-519.

  • 6. Egilmez OK Kalcioglu MT. Genetics of Nonsyndromic Congenital Hearing Loss. Scientica (Cairo). 2016;2016:7576064.

  • 7. Paludetti G1 Conti G DI Nardo W et al. Infant hearing loss: from diagnosis to therapy. Official Report of XXI Conference of Italian Society of Pediatric Otorhinolaryngology. Acta Otorhinolaryngol Ital. 2012;32:347-370.

  • 8. Jovankovičová A Staník R Kunzo S Majáková L Profant M. Surgery or implantable hearing devices in children with congenital aural atresia: 25 years of our experience. Int J Pediatr Otorhinolaryngol. 2015;79:975-979.

  • 9. Arndt S Prosse S Laszig R Wesarg T Aschendorff A Hassepass F. Cochlear implantation in children with single-sided deafness: does aetiology and duration of deafness matter? Audiol Neurootol. 2015;20(Suppl 1):21-30.

  • 10. 10 Boyd PJ. Potential benefits from cochlear implantation of children with unilateral hearing loss. Cochlear Implants Int. 2015;16:121-136.

  • 11. Molini E Calzolaro L Lapenna R Ricci G. Universal newborn hearing screening in Umbria region Italy. Int J Pediatr Otorhinolaryngol. 2016;82:92-97.

  • 12. Chen MM Oghalai JS. Diagnosis and Management of Congenital Sensorineural Hearing Loss. Current Treatment Options in Pediatrics. 2016;2:256-265.

  • 13. Korver AM Smith RJ Van Camp G et al. Congenital hearing loss. Nat Rev Dis Primers. 2017;3:16094.

  • 14. Tharpe AM Gustafson S. Management of Children with Mild Moderate and Moderately Severe Sensorineural Hearing Loss. Otolaryngol Clin North Am. 2015;48:983-994.

  • 15. Singleton AJ Waltzman SB. Audiometric Evaluation of Children with Hearing Loss. Otolaryngol Clin North Am. 2015;48:891-901.

  • 16. François M Dehan E Carlevan M Dumont H. Use of auditory steady-state responses in children and comparison with other electrophysiological and behavioral tests. Eur Ann Otorhinolaryngol Head Neck Dis. 2016;133:331-335.

  • 17. Martínez-Cruz CF García Alonso-Themann P Poblano A Cedillo-Rodríguez IA. Hearing and neurological impairment in children with history of exchange transfusion for neonatal hyperbilirubinemia. Int J Pediatr. 2014;2014:605828.

  • 18. Akinpelu OV Waissbluth S Daniel SJ. Auditory risk of hyperbilirubinemia in term newborns: a systematic review. Int J Pediatr Otorhinolaryngol. 2013;77:898-905.

  • 19. Beswick R Driscoll C Kei J. Monitoring for postnatal hearing loss using risk factors: a systematic literature review. Ear Hear. 2012;33:745-756.

  • 20. Cristobal R Oghalai JS. Hearing loss in children with very low birthweight: current review of epidemiology and pathophysiology. Arch Dis Child Fetal Neonatal Ed. 2008;93:F462-F468.

Search
Journal information
Metrics
All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 842 553 16
PDF Downloads 354 231 5