Takotsubo Syndrome: Is This a Common Occurrence in Elderly Females after Hip Fracture?
Article Category: Research Article
Published Online: Aug 11, 2020
Page range: 146 - 151
Received: Jan 24, 2020
Accepted: May 31, 2020
DOI: https://doi.org/10.2478/jccm-2020-0022
Keywords
© 2020 Carlo Rostagno, Gianluca Polidori, Alice Ceccofiglio, Alessandro Cartei, Alberto Boccaccini, Adriano Peris, Gaia Rubbieri, Roberto Civinini, Massimo Innocenti, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Background
The prevalence of Takotsubo syndrome in hip fracture is not known.
Methods
Hip fracture patients were evaluated in a multidisciplinary unit. Patients with ECG abnormalities and increased troponin I values at the time of hospital admission were included in the study Follow-up was clinical at 30 days and by telephonic interview at one year.
Results
Between October 1st 2011 to September 30th 2016, 51 of 1506 patients had preoperative evidence of myocardial damage. Eight, all females, fulfilled the Mayo criteria for Takotsubo syndrome, six had no coronary lesions. Hip surgery was uneventful, and all eight were alive at thirty days, and seven of these were still alive after one year. Forty-three patients had myocardial infarction: mortality at thirty days and one year were 11% and 44% (p<0.0001, Student’s t-test; log-rank test).
Conclusion
At least 15% of patients with hip fracture and preoperative myocardial damage had Takotsubo syndrome. They were all elderly females. Contrary to myocardial infarction, Takotsubo syndrome has a favourable long term prognosis.