What does the water inside the brain tell us? Diffusion tensor imaging

Open access


The brain consist of about 75 percent water. Diffusion tensor imaging (DTI) is an advanced magnetic resonance (MR) technique imaging that has been developed for diagnostic and research in medicine. It can be use DTI tractography to better understand degenerating axons of white matter lesions in some neurological diseases such as MS, AD, trauma, cerebral ischemia, epilepsy, brain tumors and metabolic disorders.

If the inline PDF is not rendering correctly, you can download the PDF file here.

  • 1. Fields RD. Change in the Brain’s White Matter: The role of the brain’s white matter in active learning and memory may be underestimated. Science (New York NY). 2010;330(6005): 768-769.

  • 2. Le Bihan D Mangin JF Poupon C. et al: Diffusion tensor imaging: concepts and applications. J Magn Reson Imaging 2001;13:534-546.

  • 3. Mukherjee P Berman JI Chung SW Hess CP Henry RG. Diffusion tensor MR imaging and fiber tractography: theoretic underpinnings. AJNR Am J Neuroradiol. 2008a;29(4):632-41.

  • 4. Bammer R Acar B Moseley ME. In vivo MR tractography using diffusion imaging. Eur J Radiol. 2003;45(3):223-34.

  • 5. de Figueiredo EH Borgonovi AF Doring TM. Basic concepts of MR imaging diffusion MR imaging and diffusion tensor imaging. Magn Reson Imaging Clin N Am. 2011;19(1):1-22.

  • 6. Sundgren PC Dong Q Gómez-Hassan D Mukherji SK Maly P Welsh R. Diffusion tensor imaging of the brain: review of clinical applications. Neuroradiology. 2004;46(5):339-50.

  • 7. Huisman TAGM. Diffusion-weighted and diffusion tensor imaging of the brain made easy. Cancer Imaging. 2010;10:163-171.

  • 8. Mukherjee P Chung SW Berman JI Hess CP Henry RG. Diffusion tensor MR imaging and fiber tractography: technical considerations. AJNR Am J Neuroradiol. 2008b;29(5):843-52.

  • 9. Mori S van Zijl PC. Fiber tracking: principles and strategies-a technical review. NMR Biomed 2002;15:468-80

  • 10. Conturo TE Lori NF Cull TS et al. Tracking neuronal fiber pathways in the living human brain. Proc Natl Acad Sci USA 1999;96:10422- 27

  • 11. Catani M Howard RJ Pajevic S et al. Virtual in vivo interactive dissection of white matter fasciculi in the human brain. Neuroimage 2002;17:77-94

  • 12. Acer N Dolu N Zararsız G Dogan MS Gümüş K Özmen S Kara AY Soysal H Per H Bilgen M. Anatomical characterization of ADHD using an atlas-based analysis: A diffusion tensor imaging study. Eurobiotech J 2017; 1: 46-56

  • 13. Acer N Bastepe-Gray S Sagiroglu A Gumus KZ Degirmencioglu L Zararsiz G Ozic MU. Diffusion tensor and volumetric magnetic resonance imaging findings in the brains of professional musicians. J Chem Neuroanat. 2018;88:33-40.

  • 14. Smith SM Jenkinson M Johansen-Berg H et al. Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. Neuroimage 2006;31:1487-505

  • 15. Jones DK Symms MR Cercignani M et al. The effect of filter size on VBM analyses of DT-MRI data. Neuroimage 2005;26:546-54.

Journal information
All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 297 263 23
PDF Downloads 204 176 11