Effect of Tobacco Smoke Condensates on Ascorbate

Abstract

Ethanolic extracts of tobacco and tobacco smoke contain compounds capable of accelerating the oxidation of ascorbate. Using a polarographic technique, smoke from cigarettes, cigars and pipe were examined for oxidising properties. Smoke from Virginia cigarettes showed greater activity than that from blended cigarettes, while smoke from cigars and pipes had even lower activity. The reaction of ascorbate and smoke has been shown by EPR to involve a radical intermediate.

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  • 1. Benedict, R. C., Strange, E. D., and Lakritz, L.: 23rd Tobacco Chemists' Research Conference, Philadelphia, Penn., 1969.

  • 2. Benedict, R. C., Lakritz, L., Strange, E. D., and Stedman, R. L.: Chem. & Incl., Soo, 13 June 1970.

  • 3. Bielski, B. H. J ., and Alien, A. 0.: J. Am. Chem.Soc. 92 (1970) 3793·

  • 4. Bilimoria, M. H., and Nisbet, M. A.: Beitr. Tabakforsch. 6 (1971) ???.

  • 5. Calder, J. H., Curtis, R. C., and Fore, H.: The Lancet 1963 (:r.) 556. '

  • 6. Edgar, J. A.: Experientia 25 (1969) 1214.

  • 7. Edgar, J. A.: Nature 22.7 (1970) 24.

  • 8. Hagopian, M.: Environ. Sci. Technol. 3 (1969) 567.

  • 9. Hagopian, M., and Rosenkrantz, H.: Proc. Soc. Exp.Bioi. Med. 130 (1969) 1234.

  • 10. Sebrell, W. H., and Harris, R. S. (editors): The vitamins, Chemistry, physiology, pathology, methods, Vol. '1, Academic Press, 196].

  • 11. Szent-GyOrgyi, A.: Science 149 (1965) 34·

  • 12. Szent-GyOrgyi, A.: Science '16'1 (1968) 988.

  • 13. Taber, R. 1., and larson, P. S.: Arch. lnt. Pharmacodyn. 15'1 (1964) 243·

  • 14. Yamazaki, 1., Mason, H. S., and Piette, L.: J. Biol. Chem. 235 (1960) 2444·

  • 15. Yamazaki, 1., and Piette, L.: Biochem. Biophys.Acta 50 (1961) 62.

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