New Drug Delivery Systems Concept in Anaesthesia and Intensive Care—Controlled Release of Active Compounds

Anca Dinu 1 , Mihai Sandesc 1 , Sonia Elena Popovici 2 , Razvan Gabriel Dragoi 1 , Amaricai Elena 1  and Tiberiu Bratu 1
  • 1 Faculty of Medicine, “Victor Babes” University of Medicine and Pharmacy, 300041, Timisoara, Romania
  • 2 Clinic of Anaesthesia and Intensive Care, Emergency County Hospital “Pius Brinzeu”, , 300723, Timisoara, Romania


With time, medical and pharmaceutical research has advanced significantly. However, one of the major issues is how to administer the active substance. Among these, it counts over-or under-dosage of the active substance, low response to treatment, or increased clinical risk of the patient. An innovative method able to avoid these obstacles is represented by controlled release systems for active substances. The interest for these systems came with allowing encapsulation in the antibiotic release matrices, local anesthetics, protein or other substances. Moreover, a number of such vehicles are now available to release controlled substances used predominantly in the anesthesia and intensive care unit.

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