Loss of mass and performance in skeletal muscle tissue: a continuum model

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Abstract

We present a continuum hyperelastic model which describes the mechanical response of a skeletal muscle tissue when its strength and mass are reduced by aging. Such a reduction is typical of a geriatric syndrome called sarcopenia. The passive behavior of the material is described by a hyperelastic, polyconvex, transversely isotropic strain energy function, and the activation of the muscle is modeled by the so called active strain approach. The loss of ability of activating of an elder muscle is then obtained by lowering of some percentage the active part of the stress, while the loss of mass is modeled through a multiplicative decomposition of the deformation gradient. The obtained stress-strain relations are graphically represented and discussed in order to study some of the effects of sarcopenia.

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Journal Information


CiteScore 2017: 0.88

SCImago Journal Rank (SJR) 2017: 0.324
Source Normalized Impact per Paper (SNIP) 2017: 0.532

Mathematical Citation Quotient (MCQ) 2017: 0.38

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