Genetic diversity of the long terminal repeat of bovine leukaemia virus field isolates
, , and | Dec 30, 2015
Published Online: Dec 30, 2015
Page range: 447 - 450
Received: Nov 25, 2015
Accepted: Dec 04, 2015
DOI: https://doi.org/10.1515/bvip-2015-0065
Keywords
© National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
In this study the sequences of the long terminal repeat (LTR) of field isolates of the bovine leukaemia virus (BLV) were analysed. These isolates came from emerging cases of BLV infection in cattle from herds having BLV-free status. We found several sequence variations within regulatory motifs in the LTRs like GRE, DAS and interferon binding site. These mutations can possibly affect transcriptional activity of the virus, leading to its silencing.