Expression of CD3, CD4, CD8, CD21, and MHC II lymphocyte antigens and serum IL-10 concentration in dogs with atopic dermatitis complicated by purulent dermatitis

Dog blood samples were analysed cytometrically and immunoenzymatically. In dogs with atopic dermatitis complicated by purulent dermatitis, the percentage of lymphocytes with CD8, CD21 antigens, as well as IL-10 concentration in serum were significantly higher than in healthy dogs. The results indicate that immunosuppression induced by the activity of an infectious agent plays an important role at this stage of the disease. This thesis was further confirmed by a high positive correlation between MHC II CD3, CD4, and CD21expression and a negative correlation between cells with MHC II and CD8 lymphocytes.