Tricuspid Dysplasia in Dogs

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The aim of the study was to estimate prevalence of tricuspid dysplasia (TD) in dogs with respect to breed, age, sex, clinical signs, and echocardiographic findings and to compare this data with literature. TD was found in 15 dogs (6.5% of congenital cardiac disease) of 215 dogs with congenital heart defects. All dogs had right heart enlargement on thoracic radiographs, echocardiography, and electrocardiography. Doppler echocardiography revealed tricuspid valve regurgitation. Seven dogs presented no clinical symptoms to date. TD took the form of Ebstein anomaly in all Labrador Retrievers, one Boxer, and one German Shepherd dog. TD predominated in males (11 males vs. three females). The body weight of the affected dogs, with the exception of the Miniature Schnauzer, exceeded 20 kg. Two dogs (Boxer and Bull Terrier) had additional congenital cardiac lesions in the form of mitral valve dysplasia. The most affected breeds in the study were the Labrador Retriever and Boxer.

1. Andelfinger G., Wright K.N., Lee H.J., Siemens L.M., Benson D.W.: Canine tricuspid valve malformation, a model of human Ebstein anomaly, maps to dog chromosome 9. J Med Genet 2003, 40, 320-324.

2. Ammash N.M., Warnes C.A., Connolly H.M., Danielson G.K., Seward J.B.: Mimics of Ebstein’s anomaly. Am Heart J 1997, 134, 508-513.

3. Attie F., Rosas M., Rijlaarsdam M., Buendia A., Zabal C., Kuri J., Granados N.: The adult patients with Ebstein’s anomaly: Outcome in 72 unoperated patients. Medicine 2000, 79, 63-69.

4. Bernard C.N., Schrire V.: Surgical correction of Ebstein’s malformation with prosthetic tricuspid valve. Surgery 1963, 54, 302-308.

5. Bialostozky D., Medrano G., Muňoz-Castellanos L., Contreras R.: Vectorcardiographic study and anatomic observations in 21 cases of Ebstein’s malformation of the tricuspid valve. Am J Cardiol 1972, 30, 354-361.

6. Chetboul V., Tran D., Carlos C., Tessier D., Pouchelon I.L.: Congenital malformations of the tricuspid valve in domestic carnivores: A retrospective study of 50 cases. Schweiz Arch Tierheilkd 2004, 146, 265-275.

7. Correa-Villasenor A., Ferencz C., Neil C.A., Wilson P.D., Boughman J.A.: Ebstein’s malformation of the tricuspid valve: genetic and environmental factors. Teratology 1994, 50, 137-147.

8. Diana A., Guglielmini C., Acocella F., Valerio F., Cipone M.: Chylothorax associated with tricuspid dysplasia and atrial septal defect in a bullmastiff. J Am Anim Hosp Assoc 2009, 45, 78-83.

9. Eyster G.E., Anderson L., Evans A.T., Chaffe A., Bender G., Johnston J., Muir W., Blanchard G.: Ebstein’s anomaly: a raport of 3 cases in the dog. J Am Vet Med Assoc 1977, 170, 709-713.

10. Famula T.R., Siemens L.M., Davidson A.P., Packard M.: Evaluation of the genetic basis of tricuspidal valve dyplasia in Labrador retrievers. Am J Vet Res 2002, 63, 816-820.

11. Gregori T., Gomez Ochoa P., Quintavalla F., Mavropoulou A., Quintavalla C.: Congenital heart defects in dogs: a double retrospective study on cases from University of Parma and University of Zaragoza. Ann Fac Med Vet Parma 2008, 28, 79-90.

12. Hoffmann G., Amberger C.N., Seiler G., Lombard C.W.: Tricuspid valve dysplasia in fifteen dogs. Schweiz Arch Tiercheilkd 2000, 142, 268-77.

13. Jost Ch.H.A., Connolly H.M., O’Leary P.W., Warnes C.A., Tajik A.J., Seward J.B.: Left heart lesions in patients with Ebstein anomaly. Mayo Clin Proc 2005, 80, 361-368.

14. Kornreich B.G., Moise N.S.: Right atrioventricular valve malformation in dogs and cats: an electrocardiographic survey with emphasis on splintered QRS complexes. J Vet Int Med 1997, 11, 226-230.

15. Lisowska A., Sobkowicz B., Musiał W.J., Skibińska E.: Congenital tricuspid valve dysplasia in a patient with advanced heart failure. Kardiol Pol 2006, 63, 201-203.

16. Liu S.K., Tilley L.P.: Dysplasia of the tricuspid valve in the dog and cat. J Am Vet Med Assoc 1976, 169, 623-630.

17. de Madron E., Kadish A., Spear J.F., Knight D.H.: Incessant atrial tachycardias in a dog with tricuspid dysplasia. Clinical management and electrophysiology. J Vet Int Med 1987, 1, 163-169.

18. Riesen S.C., Kovacevic A., Lombard C.W., Amberger C.: Echocardiographic screening of purebred cats: an overview from 2002 to 2005. Schweiz Arch Tierheilkd 2007, 149, 73-76.

19. Sousa M.G., Gerardi D.G., Alves R.O., Camacho A.A.: Tricuspid valve dysplasia and Ebstein’s anomaly in dogs: case report. Arq Bras Med Vet Zootec 2006, 58, 762-767.

20. Tidholm A.: Retrospective study of congenital heart defects in 151 dogs. J Small Anim Pract 1997, 38, 94-98.

Bulletin of the Veterinary Institute in Pulawy

The Journal of National Veterinary Research Institute in Pulawy

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