Diagnostic and Therapeutic Approach to HIVKaposi’s Sarcoma Patients-Case Report

Open access

Summary

Background/Aim: The Acquired Immune Deficiency Syndrome (AIDS) is an immunologic entity, which is due to an RNA virus. AIDS is relatively easy transmitted and has a poor prognosis. The main mechanism of this Syndrome is characterized by the destruction and diminishing of T4 lymphocytes or helper/suppressor T-cells. Kaposi’s sarcoma is a neoplasm due to human herpes HHV-8. Kaposi’s sarcoma is one of the entities that determines the disease of AIDS. Kaposi’s sarcoma appears as skin lesions and attacks the oral cavity and lymph nodes.

Case report: A male patient, with HIV-syndrome, was referred to the Special Infection Clinic of the University Hospital with a chief complaint of having two lesions, in the oral cavity and in the right ear. The histological report revealed the diagnosis of vascular tumor having morphological and immuno-histochemical characteristics compatible with Kaposi’s sarcoma.

Conclusions: The doctor must be suspicious when lesions are observed, particularly in the oral cavity. A biopsy must be taken in order to obtain the correct diagnosis and examine the possibility of the presence of Kaposi’s sarcoma or AIDS.

If the inline PDF is not rendering correctly, you can download the PDF file here.

  • 1. Goldman C. Medicine (25th ed). Elsevier 2015.

  • 2. Neville BW Damm DD Allen CM Bouquot JE. Oral and Maxillofacial Pathology (2nd ed). Philadelphia: Saunders 2002.

  • 3. Sri Kenath A Ramesh Kuman A Sonika V Sri Sennath A Arul J. Oral Kaposi’s Sarcoma: Sole presentation in HIV seropositive patient. J Nat Sci Bio Med 2015;6:459-461.

  • 4. SW Goldblum JR. Enzinger and Weiss’s Soft Tissue Tumors (4th ed). Philadelphia: Mosby-Harcourt 2001; pp: 938-947.

  • 5. Kaposi M. Idiopanthisches multiples Pigmentsarkom der Haut. Arch Dermatol Syph 1872;4:265-276.

  • 6. Barnes L Eveson JW Reichart P Sidransky D. Classification of Tumors. Pathology and Genetics of Head and Neck Tumors. World Health Organization; Lyon: IARC Press 2005; pp:193-194.

  • 7. Kennedy-LeJeune E Cataldo VD. Kaposi’s Sarcoma of the Oral Cavity. N Engl J Med 2017;376:1268.

  • 8. Bortoluzzi MC Goncalves RCG de Freitas CM Ramacciato JC de Oliveira Jabur R. Classic Kaposi’s Sarcoma (Non HIV Associated) of Oral Cavity. A case report. Braz J Oral Sci 2017;16:e17062.

  • 9. Vieira F Somerville J Kenneth LK. Oral Kaposi’s Sarcoma in HIV Positive Patients. A Case Report and Review of Literature. J Aids Clin Res 2014;5:9.

  • 10. Brenner B Rakowsky E Katz A Gutman H Sulkes A Schacter J Fenig E. Tailoring treatment for classical Kaposi’s sarcoma: comprehensive clinical guidelines. Int J Oncol 1999;14:1097-1102.

  • 11. Fatahzadeh M Schwartz RA. Oral Kaposi’s Sarcoma: a review and update. Int J Dermatol 2013;52:666-672.

  • 12. Marx RE Stern D. Oral and Maxillofacial Pathology: A Rationale for Diagnosis and Treatment. 2nd ed. Chicago: Quintessence Publishing Company 2012; pp: 508-512.

  • 13. Krown SE Metroka C Wentz JC. Kaposi’s sarcoma in the acquired immune deficiency syndrome: A proposal for uniform evaluation response and staging criteria. AIDS Clinical Trials Group Oncology Committee. J Clin Oncol 1989;7:1201-1207.

  • 14. Joshi U Ceena DE Ongole R Sumanth KN Boaz K Jeena Priy K et al. AIDS related Kaposi’s sarcoma presenting with palatal and eyelid nodule. J Assoc Physians India 2012;60:50-53.

Search
Journal information
Metrics
All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 71 71 22
PDF Downloads 74 74 22