One cutting order may require several lies and markers to achieve optimal efficiency and selection of right Lay Plan is one of the major challenges in cutting section, in a way to lead in fabric economy and reduced costs. The main purpose of this paper is to determine the best solution of lay plan and its influence, in the cutting room, starting from the analysis of the lay indicators calculations. We have studied an order with 200 jackets, with specific sizes. Markers are made by Gemini CAD (Gemini Cut Plan and Gemini Nest Expert). From Gemini CAD, we have taken different solutions of lay plans and chose the three best of them (lay plans that have a smaller number of lies, plies etc.), and then, for three best solutions are calculated lay indicators. From this calculation, we have determined the best solution of lay plan. The order to study has 5 different fabrics, so the calculations are made for each of them, and in the end are combined, in a way to have conclusions for an order in general. Best solution of lay plans combination, resulted one which had a better weighted efficiency and a low lay consumption.