N-Terminal Pro-B-Type Natriuretic Peptide – Prognstic Value for Death Within 24 Hours in Severe Polytrauma Patients with Chest Trauma

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Abstract

Patients with multiple trauma with thoracic trauma have higher death rates compared to multiple trauma patients without thoracic trauma, mainly because of cardiac injury. We investigated the 24 hours prognostic value of NT-proB-type Natriuretic Peptide (Nt-ProBNP) in polytraumatised patients with thoracic trauma.

The study group was composed of 33 patients, 25 males and 8 females. During the study, the endpoint, which was death in the first 24 hours after admission was observed in 33% of the patients (11 patients).

Using a cut-off point of 125 pg/ml, the sensitivity of the test was 100% and the specificity was 59.09%.

Accoring to the results of the study, NT-ProBNP proves that it might be useful in detecting patients with a bad prognosis, the analyzed enzyme having the capacity of identifying polytrauma patients with thoracic trauma that have high risk of death in the first 24 hours after admission.

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ARS Medica Tomitana

The Journal of "Ovidius" University of Constanta

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