The Role of Eosinophilic Cationic Proteins, Total IgE and Eosinophilia in Children with Bronchial Hyperresponsiveness

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Bronchial hyperreactivity (HRB), is defined as an excessive bronchial constriction that acts as an exaggerated bronchoconstrictor of the airways. This occurs as a secondary action of a nonspecific stimuli.

Taking as a starting point asthmatic patient, as the patient responds by bronchoconstriction action of various stimuli, the concept of bronchial hyperractivity gradually began to take shape. Bronchial hyperractivity (HRB) can be considered a major, heterogeneous phenomenon, depending on several conditions, in term of etiology and which gathers the features of a genuine syndrome if we consider the complexity of the mechanisms which produce and countless clinical implications.

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